Genomic methods aid study of Seattle 2017-2022 Shigella outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle from 2017 to 2022 enabled scientists to retrace its origin and spread. Additional analysis of the gut pathogen and its transmission patterns helped direct approaches to testing, treatment, and public health responses. The aim of the study was to better understand the community transmission and spread of antimicrobial resistance and to treat these multi-drug resistant infections more effectively.