AstraZeneca and Hutchmed Initiate P-III SAMETA Trial of Imfinzi (durvalumab) + Orpathys (savolitinib) for Advanced Papillary Renal Cell Carcinoma

November 1, 2021 Auto Bot AstraZeneca, Clinical Trials, durvalumab, Hutchmed, Imfinzi, P-III 0

Shots:

  • The companies initiate P-III SAMETA study to evaluate the efficacy and safety of Hutchmed’s savolitinib (MET tyrosine kinase inhibitor) + AstraZeneca’s Imfinzi (PD-L1 inhibitor) in treatment-naïve patients with MET-driven advanced PRCC. The first patient was dosed on Oct 28, 2021
  • The 1EPs of the study is m-PFS & other EPs include m-OS, ORR, DoR, 6 & 12mos. DCR, time to second progression (PFS2), safety, PK, and QoL
  • In 2011, the companies collaborated to jointly develop & commercialize savolitinib where Hutchmed will lead marketing authorization, manufacturing & supply of the therapy in China & AstraZeneca is responsible for the commercialization globally

Click here to­ read the full press release/ article | Ref: Globenewswire | Image: AstraZeneca

The post AstraZeneca and Hutchmed Initiate P-III SAMETA Trial of Imfinzi (durvalumab) + Orpathys (savolitinib) for Advanced Papillary Renal Cell Carcinoma first appeared on PharmaShots.