As demand for menopause drugs soars, we trace the oestrogen production line from Chinese soya bean fields to European pharmacy shelves
In the centre of the factory stand 31 reactors: giant metal globes that can hold up to 10,000 litres of liquid each. Every week, gleaming stainless steel drums arrive by truck at this plant on the outskirts of Oss, in the Netherlands. Their contents are poured into the reactors through a funnel, dissolved, and then heated to boiling point. Standing by one of the vast containers, the factory manager, Robert Dam, compares it to a “cooking pot”. Peering inside, we can see the light liquid bubbling away.
At Dam’s factory, a white powder distilled from soya beans and shipped from China is turned into a precious commodity: strong synthetic oestrogen. The plant at Oss, owned by the Dutch subsidiary of South Africa’s largest drugmaker Aspen Pharmacare, produces the most potent variant of oestrogen, known as oestradiol, destined for the UK market. It will be added to gels, sprays and patches used by more than 1 million women in Britain to manage the symptoms of menopause.
