AstraZeneca Reports Updated Data from the P-III (ADJUVANT BR.31) Study of Imfinzi to Treat Non-Small Cell Lung Cancer

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The P-III (ADJUVANT BR.31) study, funded by the Canadian Cancer Trials Group, assessed adj. Imfinzi vs PBO among Stage IB (≥4cm), II or IIIA NSCLC patients (n=1,415) post complete tumor resection, with/without adj. CT
Study did not reach its 1EP of DFS specifically in patients with PD-L1-expressing tumors. The safety profile aligned with the previous studies without any new safety outcomes; data will be highlighted at future conferences
In addition, Imfinzi is further being assessed under the PACIFIC-4 study alone or in combinations for inoperable or unresected Stage I-II NSCLC as well as PACIFIC-5, 8 and 9 for Stage III NSCLC

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