Astellas Collaborates with Poseida Therapeutics to Develop New Allogeneic Cell Therapies in Oncology

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Astellas reported that its subsidiary, Xyphos Biosciences, & Poseida have signed a research collaboration & license agreement for developing new convertible CAR products using each company’s expertise
Under the collaboration, Poseida’s allogeneic CAR-T platform & Xyphos’ ACCEL technology will be merged to create a single CAR-T construct for 2 convertible CAR product candidates addressing solid tumors
Poseida will obtain $50M upfront, a total of $550M incl. development & sales milestones plus contingency payments along with low double-digit tiered royalties as a percentage of net sales. Furthermore, Xyphos will cover Poseida’s research costs & handle future product development & commercialization

Ref: Astellas | Image: Astellas

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