BMS’ P-III (CheckMate -8HW) Study of Opdivo (nivolumab) + Yervoy (ipilimumab) for MSI-H/dMMR mCRC Attains Primary Endpoint


The company’s P-III (CheckMate -8HW) study met the dual 1EP of PFS in the Opdivo + Yervoy vs CT for the 1L treatment while it continues to evaluate the second dual 1EP of PFS for Opdivo + Yervoy vs Opdivo monotx. for all lines of therapy along with 2EPs incl. OS
The safety profile of Opdivo + Yervoy combination remained consistent and manageable, with no new safety signals identified, aligning with previously reported data
The P-III (CheckMate -8HW) study compares Opdivo + Yervoy and Opdivo monotx. or investigator’s choice CT in patients with MSI-H/dMMR metastatic colorectal cancer (mCRC)

Ref: BMS | Image: BMS

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