BridgeBio Pharma Partners with Kyowa Kirin to Develop and Commercialize Infigratinib to Treat Skeletal Dysplasias in Japan

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Kyowa Kirin signed an agreement with BridgeBio’s affiliate, QED Therapeutics under which, Kyowa Kirin received an exclusive license to develop & commercialize infigratinib to treat ACH, hypochondroplasia & other skeletal dysplasias across Japan
As per the agreement, BridgeBio will receive an up front payment of $100M & is eligible to receive potential milestone-based payments, plus high-twenties percent royalties
Infigratinib (small molecule FGFR3 inhibitor) is currently being evaluated in a P-III (PROPEL 3) clinical trial for safety & efficacy among children & adolescents with ACH. Additionally, BridgeBio also expects to initiate an observational study (ACCEL) evaluating infigratinib in hypochondroplasia by H1’24

Ref: BridgeBio | Image: BridgeBio

Related News:- Kyowa Kirin to Acquire Orchard Therapeutics for ~$477.6M

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