Shionogi Partners with Maze Therapeutics for MZE001’s Rights to Treat Pompe Disease

Shots:

Following the completion of transaction and expiry of 30-day waiting period (as per US HSR Act), Shionogi and Maze Therapeutics have concluded an exclusive worldwide license agreement of MZE001, being developed for Pompe disease
As per the agreement, Shionogi has obtained exclusive global rights of MZE001 along with related programs & IP by paying $150M up front and undisclosed development, regulatory & commercial milestones plus tiered royalties   
MZE001 is a GYS1 enzyme targeting small molecule, reducing muscle glycogen concentration. The P-I study suggests it as monotx. or as add-on therapy with enzyme replacement to treat Pompe disease

Ref: Shionogi | Image: Shionogi

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