BMS Highlights Data from the P-I/II Study of Krazati Plus Cetuximab to Treat Locally Advanced or Metastatic Colorectal Cancer at the AACR 2024

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BMS has highlighted results from the P-I/II (KRYSTAL-1) trial arms assessing the safety & effectiveness of Krazati + cetuximab for previously treated KRASG12C mutated locally advanced or metastatic colorectal cancer (CRC) patients at the AACR 2024 and published in Cancer Discovery
The study, with a median follow-up of 11.9mos. among 94 patients, demonstrated ORR of 34%, mPFS of 6.9mos., mOS of 15.9mos., mDoR of 5.8mos. and 85% of patients experienced disease control
In Feb 2024, the US FDA accepted and granted priority review to the company’s sNDA of Krazati + cetuximab for previously treated KRASG12C-mutated locally advanced or metastatic CRC patients with the decision anticipated in Jun 2024

Ref: BMS | Image: BMS

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