Soy Phytoestrogens for Menopausal Symptoms
Does soy food consumption explain why Japanese women appear to be so protected from hot flash symptoms? When women hit menopause and their ovaries shut down, the […]
cancer
AstraZeneca’s Ultomiris; HebaBiz’s Siroquine; Pfizer’s XELJANZ; Bristol Myers Squibb’s Opdivo; and Masimo’s PVi
AstraZeneca’s Newly Occupied Alexion Hits Rock Bottom After Ultomiris (Ravulizumab) Fails to Show Efficacy in Patients with Amyotrophic Lateral Sclerosis AstraZeneca’s 39 billion USD complete […]
Pfizer makes big move in blood cancers with $2.3B Trillium acquisition
Though Gilead Sciences leads the group of companies developing immunotherapies that target the cancer protein CD47, Pfizer contends that molecules it is getting through the […]
Illumina’s Grail buyout beats deadline, but legal and regulatory hurdles remain
In closing its Grail acquisition before U.S. and European regulators sign off, Illumina is taking a chance the deal will pass regulatory muster. It’s a […]
FDA decision for GSK drug opens door to treatment of more cancer patients
GlaxoSmithKline drug Jemperli is now FDA approved for treating solid tumors throughout the body as long as they have a particular genetic signature. Expanding the […]
HiberCell’s Genuity buyout brings $100M, plus alliances with Ionis and AbbVie
Startup HiberCell has acquired Genuity Science, a marriage that brings together two companies that apply AI and machine learning to drug research. HiberCell says Genuity […]
Sesen Bio says rejected bladder cancer drug may need new clinical trial
For much of this summer, Sesen Bio said all of the FDA’s communications pointed toward regulatory approval for the biotech’s bladder cancer drug. Though Sesen […]
Merck drug acquired in $1B deal approved to treat tumors sparked by rare disease
FDA approval of the Merck drug, belzutifan, covers treatment of tumors caused by von Hippel-Lindau disease, an inherited disorder associated with several types of cancer. […]
Noncoding RNA Therapies
I was mentioning the number of unusual therapeutic modes that are being explored these days, and one of those is (broadly) RNA-based approaches. The ones […]
Second FDA clinical hold for Aprea cancer drug cites safety data in another study
For the second time in a week, the FDA placed a clinical hold on an Aprea Therapeutics cancer drug. The biotech said the agency cited […]
The Dangers of Talcum Powder
What role does diet and baby powder play in the development of fibroids and ovarian cancer? If you randomly select a group of women and ultrasound their […]
Breast cancer drug approved for NHS after maker agrees discount
Reversal of earlier rejection by Nice of abemaciclib – known as Verzenios – is welcomed by campaigners A breast cancer drug that was rejected for […]
Kite Signs a License Agreement with Appia to Develop Allogeneic Cell Therapies for the Treatment of Cancer
Shots: Appia Bio to receive $875M as an up front, equity investment, and milestone along with royalties. Kite will be responsible for the development, manufacturing, […]
Can mRNA vaccines do for cancer what they did with Covid-19?
The short answer is that cancer vaccines represent no silver bullet but, in combination with other immunotherapy and drug cocktails, can prove potent.
A New Pathway To Kill Resistant Breast Cancer
As all the recent news about protein folding should make clear, there are a lot of ways for any given protein sequence to come together […]
5 days, 11 life science IPOs & more than $1.3B in new capital
Of the 20 companies that went public in the last week of July, 11 of them represent some aspect of the life sciences. The tally […]
Eli Lilly hands Kumquat Biosciences $70M to kick off cancer drug R&D alliance
Eli Lilly is beginning a research alliance discovering and developing small molecules that stimulate immune responses against cancer. If drugs from the partnership reach the […]
Dr. Greger’s Daily Dozen Healthiest of Healthy Foods
In my book How Not to Die, I center my recommendations around a Daily Dozen checklist of everything I try to fit into my daily routine. In my book How Not […]
Amgen adds antibody assets and R&D tech with $900M Teneobio acquisition
Amgen is paying $900 million up front to acquire Teneobio, a biotech with technology for discovering and developing antibody drugs. Though Amgen already has its […]
FDA rejects Incyte cancer drug, asking for more data to show clinical benefit
An Incyte drug developed as a treatment for a rare type of anal cancer has fallen short of FDA approval. The regulator said it needs […]
Is medical cannabis really a magic bullet?
Research increasingly suggests that extracts from the plant are effective in treating pain, anxiety, epilepsy and more, but experts still preach caution around recreational use […]
Radiation and Immunotherapy Together
Cancer immunotherapy has been a huge topic in recent years, and deservedly so. But there are some types of tumors that respond much better than […]
Frontier Medicines raises $88M for R&D, including potential rival to Amgen cancer drug
Cancer drug developer Frontier Medicines already has a research partnership with AbbVie. Now the preclinical-stage biotech has raised $88.5 million for its own pipeline, including […]
Wugen unveils $172M to take natural killer cell therapies to solid tumors
Wugen, a biotech developing “off-the-shelf” natural killer and CAR T cell therapies, has raised $172 million in Series B financing. The company’s lead program has […]
A Fifty-Year-Old Cancer Drug Doesn’t Do What You Think
5-fluorouracil (5-FU) has been around a long time now (over fifty years), and it’s a standard oncology drug (particularly in colorectal treatment regimes). But try […]
Elekta to work with academics on AI-directed radiotherapy
Radiotherapy specialist Elekta has joined forces with two academic groups in the Netherlands to explore the use of artificial intelligence (AI) to deliver more effective […]
What HCPs think about health equity in cancer care
After more than a year of COVID-19 dominating health conversations, HCPs have been engaging in dialogue about continually evident disparities that many are facing in […]
Biological Dynamics leaders share vision for multi-cancer screening test as new standard of medical care
Biological Dynamics CEO Raj Krishnan and CFO Kevin Han shared what informs their vision for developing liquid biopsies to detect cancer at the earliest stages to […]
Oil Pulling for Cancer?
What evidence exists to suggest oil pulling can effectively treat serious diseases, such as paralysis, meningitis, cancer, and AIDS? I’ve produced videos on how coconut oil is safe to put on your hair […]
Seagen veteran-led ProfoundBio gets $55M to bring cancer drugs to the clinic
ProfoundBio is developing a type of targeted cancer therapy called antibody drug conjugates. As the biotech looks ahead to clinical trials, it has raised more […]
The HPV Vaccine: Access and Use in the U.S.
This factsheet discusses HPV and related cancers, use of the HPV vaccines for both females and males, and insurance coverage and access to the vaccines.
Biotech startup using AI to take guesswork out of cancer drug selection raises $70M
Xilis is developing technology that creates a living model of a patient’s tumor, then applies artificial intelligence to determine the best drug or drug combinations […]
Health Innovators: Eliot Forster, F-Star
In this episode of Health Innovators, pharmaphorum founder Paul Tunnah interviews Eliot Forster, CEO of F-Star – a clinical-stage, NASDAQ-listed biopharmaceutical company focused on transforming the […]
After a $3B exit, a biopharma veteran unveils a new company and a global focus
Led by former Viela Bio CEO Bing Yao, ArriVent Biopharma secures rights to drugs from emerging biotech hubs, then develops them for Western markets. The […]
What mRNA is Good For, And What It Maybe Isn’t
The huge success of the mRNA vaccination platform during the pandemic has set a lot of people to thinking about what comes next. Moderna and […]
New Therapy for Aggressive Prostate Cancer Improves Survival
The experimental treatment relies on radioactive molecules that seek out tumor cells, a strategy that may be useful against other cancers.
New Therapy for Aggressive Prostate Cancer Improves Survival
The experimental treatment relies on radioactive molecules that seek out tumor cells, a strategy that may be useful against other cancers.
New Therapy for Aggressive Prostate Cancer Improves Survival
The experimental treatment relies on radioactive molecules that seek out tumor cells, a strategy that may be useful against other cancers.
Novobiocin Returns? But Not as an Antibiotic.
Here’s some interesting work from Dana-Farber (earlier BioRxiv version here) that may turn into a rare example of repurposing an old drug, if it works […]
Lyell, Verve IPOs raise a combined $692M as both biotechs steer toward clinical trials
Lyell Immunopharma and Verve Therapeutics are still preclinical, but they’re bring novel genetic approaches to the treatment of cancer and cardiovascular disease. Now the two […]
Goal Attainment Scaling
What outcomes should be used to measure if a medicine is a “good” medicine? Improved survival? Improved ability to function? Few side effects? Ability to […]
GSK Signs an Agreement with iTeos to Develop and Commercialize EOS-448 for Patients with Cancer
Shots: iTeos to receive $625M up front & is eligible to receive up to ~$1.45B in milestone upon achievement of certain milestones & royalties on […]
ASCO 2021 recap: Lynparza’s lift, Grail goes on, LAG validation & more
The American Society of Clinical Oncology’ annual meeting featured news highlights from the Merck, Novartis, and other drug giants. Meanwhile, some small biotechs rode the […]
StartUPDATES: New developments from healthcare startups
Read news highlights from HeathMine, Bind Benefits, Kurome Therapeutics, and Elligo Health Research.
INVEST Precision Medicine conference kicks off today. Register now to be part of the conversation.
Register for the INVEST Precision Medicine conference, which kicks off today. Over the next three days industry experts will talk about precision medicine developments across […]
Country focus: China & APAC’s growing medical needs bring opportunities and challenges
Dr Jay Mei from Antengene tells us how the Asia Pacific region is opening up to innovative pharma companies, and gives tips for companies navigating […]
Merus eyes tumor-agnostic path for cancer drug addressing rare genetic target
Cancer drug developer Merus has encouraging early results indicating its drug can address several different types of tumors characterized by NRG1, a rare gene fusion. […]
Auris Medical pivots from hearing loss drugs, joins red hot RNA therapies field
Auris Medical has acquired Trasir Therapeutics, a startup developing technology that expands the delivery of RNA medicines to tissues beyond the liver. Going forward, Auris […]
Changing focus to cachexia may be key to improved cancer outcomes
Cachexia could be the next blockbuster area in cancer therapeutics because of its link to survival outcomes. Physician and researcher Dr. Daniel L Marks discusses […]
MorphoSys to buy Constellation Pharma in a $1.7B bet on epigenetic cancer drugs
MorphoSys is acquiring Constellation Pharmaceuticals and its late-stage myelofibrosis drug in a deal that values the epigenetics biotech at $1.7 billion. Germany-based MorphoSys will finance […]
AI Disease Modeling Supports Precision Medicine for Cancer
Precision medicine has offered a lot of hope for the treatment of cancer, as it makes it possible to tackle the multi-faceted disease with a […]
Engine Biosciences revs up $43M for AI tech that yields targeted cancer therapies
Engine Biosciences closed a $43 million Series A financing that the startup will apply to its artificial intelligence-based technology for drug discovery. The company analyzes […]
Clearing Cellular Dead Wood
For many years now, the topic of “senescent cells” has been the subject of plenty of research work. Back in the 1960s the “Hayflick limit” […]
Tomato Sauce Put to the Test for Prostate Cancer
What happened when cancer patients were given three quarters of a cup of canned tomato sauce every day for three weeks? “Occasionally…positive things happen in […]
Lycopene Supplements Put to the Test
High doses of lycopene—the red pigment in tomatoes—were put to the test to see if it could prevent precancerous prostate lesions from turning into full-blown […]
LAG-3 drugs take centre stage at ASCO, showing potential as next-gen immunotherapies
LAG-3 drugs from arch-rivals Bristol-Myers Squibb and Merck & Co look set to become talking points at this year’s ASCO conference after trial results showed […]
Numab raises $110m to develop cancer bispecific antibodies
Switzerland’s Numab has raised 100 million Swiss francs – around $110 million – in Series C financing to develop bispecific antibodies for cancer and inflammation, […]
FDA review of Lilly/Innovent’s sintilimab paves way for cut-price immunotherapy option
The FDA has accepted Eli Lilly and China’s Innovent filing for their latecomer immunotherapy sintilimab, which is expected to compete on price with rivals such […]
BMS agrees deal worth up to $1.56bn for Agenus’ TIGIT cancer drug
Bristol-Myers Squibb has paid $200 million, and promised up to $1.36 billion in “biobucks” for exclusive rights to a cancer antibody still in the labs […]
Amla (dried Indian gooseberry) vs. Lipitor for Lowering Cholesterol
Extracts of amla (Indian gooseberry) were pitted head-to-head against cholesterol-lowering statin drugs and the blood thinners aspirin and Plavix. Indian gooseberries, otherwise known as amla, […]
‘Kicking You When You’re Down’: Many Cancer Patients Pay Dearly for Parking
For cancer patients, the road from diagnosis to survivorship feels like a never-ending parade of medical appointments: surgeries, bloodwork, chemotherapy, radiation treatments, scans. The routine […]
The Most Antioxidant-Packed Whole Food
Are the apparently amazing benefits of amla—dried Indian gooseberries—too good to be true? In reference to amla, also known as the Indian gooseberry, it’s been […]
AZ/Daiichi unveil data from TNBC hopeful datopotamab deruxtecan
AstraZeneca and Daiichi Sankyo have revealed new data from datopotamab deruxtecan in triple negative breast cancer (TNBC) – and although it’s from a small patient […]
Redesign Health Spinout Jasper Health Launches AI-Driven Cancer Care Platform
What You Should Know: – Jasper Health launched today as the first end-to-end care experience that navigates, connects, and provides actionable insights throughout the cancer […]
Mayo Clinic strikes remote patient monitoring partnership with NXgenPort
Mayo Clinic is ramping up activity in the remote patient monitoring arena. Its latest move is a collaboration with biomedical technology company NXgenPort, which will […]
CRISPR Therapeutics begins natural killer cell cancer tie-up with Nkarta
Gene editing firm CRISPR Therapeutics has announced a collaboration with US biotech Nkarta to develop natural killer (NK) cell therapies for cancer. This latest agreement […]
Are Avocados Associated with Greater Risk or Reduced Risk of Cancer?
Avocado consumption can improve artery function, but what effect might guacamole have on cancer risk? In my last video about avocados, The Effects of Avocados […]
Cancer Centers: Here’s How We Can Restart Clinical Trials Today
Marie E. Lamont, President and COO of Inteliquet Biopharmaceutical companies developing cancer treatments need to restart the clinical trials shut down or delayed during the […]
Roche’s Tecentriq gets fourth European lung cancer indication
Roche’s cancer immunotherapy Tecentriq has been granted a new use by European regulators, for the first-line treatment of certain patients with metastatic non-small cell lung […]
Natural Dietary Treatments for Fibroids
The same diet that helps regulate hormones in women may also reduce exposure to endocrine-disrupting pollutants. Fibroids are the most common benign tumors in women. […]
Two new biotechs unveil $112M combined for antibody drug conjugates for cancer
The list of FDA-approved antibody drug conjugates (ADC) is growing, and two more biotech startups have emerged from stealth with new cash and new approaches […]
Two Steps to Activation
Engineering immune system cells to do what we’d like them to do is one of the big areas of medical research these days, and this […]
Tecentriq can stay as therapy for triple-negative breast cancer, FDA experts say
Roche’s Tecentriq can stay on the US market as a therapy for triple negative breast cancer, advisers to the FDA have said as part of […]
Updated guidance for cancer patients during Covid-19 may help improve outcomes
New recommendations may provide reassurance for patients and their care teams, while uniquely positioning healthcare providers to help communicate this critical information to vulnerable populations.
FDA approves under-pressure GSK’s Jemperli for endometrial cancer
The FDA has approved GlaxoSmithKline’s Jemperli (dostarlimab) immunotherapy, a drug acquired through its $5.1 billion acquisition of Tesaro, for certain patients with endometrial cancer. With […]
FDA approves GSK drug for endometrial cancer with specific genetic signature
The FDA approved GlaxoSmithKlie drug dostarlimab (Jemperli) for endometrial cancer that carries a particular genetic signature. The immunotherapy now joins Merck’s Keytruda as the checkpoint […]
Centessa plans $100m IPO to fund R&D and potential acquisitions
Centessa has announced plans for a $100m US IPO just weeks after the company launched with $250m in private backing and an R&D powerhouse driven […]
Regulatory progress for two biotechs stalls as FDA requests more information
The FDA placed a clinical hold on a KalVista Pharmaceuticals drug being readied for mid-stage studies in a rare, inherited disorder. Meanwhile, the FDA has […]
NorthShore, Sema4 set up genomics program to advance personalized treatment
The Illinois-based health system is teaming up with the analytics company to launch a genomics program, which will focus on predicting the risk of illness […]
Should You Get an Annual Physical Exam?
What are the risks and benefits of getting a comprehensive annual physical exam and routine blood testing? The model of getting an annual physical exam […]
J&J decides against Erleada+Zytiga combination prostate cancer filing
Johnson & Johnson won’t be filing a prostate cancer therapy combining its Erleada and Zytiga drugs with regulators, after a phase 3 trial showed it […]
Non-Small Cell Lung Cancer Drug Development Summit
The Non-Small Cell Lung Cancer (NSCLC) Drug Development Summit is the definitive industry-led forum for drug development in the largest solid tumor indication. This is a strategic conference designed […]
Activist investor Elliott builds stake in GSK after fresh trial upset
Activist investor Elliott Management has built a significant stake in GlaxoSmithKline, after a poor run of clinical trial results this year raised questions about management’s […]
LifePoint Health, Eon strike partnership to advance early diagnoses
Together, the Tennessee-based health system and health technology company will develop solutions to help clinicians detect diseases faster. The new agreement builds on an existing […]
C2i Genomics Raises $100M for Whole-Genome Cancer Treatment Intelligence Platform
– Cancer intelligence company, C2i Genomics announced it has raised $100M in financing from Casdin Capital, NFX, Duquesne Family Office, Section 32, iGlobe Partners, Driehaus […]
Should You Get an Annual Health Check-Up?
What are the risks and benefits of getting an annual check-up from your doctor? Physicians and patients have come to expect the annual check-up as […]
Boehringer and MD Anderson extend KRAS cancer collaboration
Boehringer Ingelheim and The University of Texas MD Anderson Cancer Center have extended and expanded a collaboration exploring medicines targeting lung cancer with KRAS mutations. […]
Gilead’s Trodelvy approved in metastatic urothelial cancer
Gilead’s Trodelvy has another string to its bow after FDA approval in patients with advanced metastatic urothelial cancer. Trodelvy (sacituzumab govitecan) has been approved for […]
AZ aims at Pfizer, GSK with potential new PARP cancer drug
AstraZeneca’s Lynparza (olaparib) blazed a trail for the new class of PARP drugs when it was approved in 2014 to treat ovarian cancer. The drug […]
Biotech startup Repertoire adds $189M to expand array of immune medicines
With two cancer programs already making progress, Repertoire Immune Medicines will use the Series B financing to expand its immune synapse research to autoimmune disorders […]
Do Cell Phones Cause Brain Tumors?
What does the world’s leading authority on carcinogens have to say about mobile phones? Do cell phones cause cancer? That’s a question billions of people […]
Sanofi spends $160M in bet that Tidal’s tech gets it to off-the-shelf CAR-T therapy
Sanofi, which already has messenger RNA R&D alliances with other companies, paid $160 million up front to acquire preclinical startup Tidal Therapeutics. The pharma giant […]
Philips, Ibex Medical Analytics Partner on AI-Powered Digital Pathology Adoption
What You Should Know: – Philips and Ibex Medical Analytics announced a strategic partnership to globally commercialize clinically proven, AI-powered digital pathology solutions. The collaboration […]
Can Cell Phone Radiation Damage Your DNA?
Do mobile phones cause brain tumors? Whenever a trillion-dollar industry is involved—whether it’s Big Food, Big Tobacco, Big Pharma, or Big Telecom—there’s so much money […]
Cardinal Health and Deep Lens Collaborate for AI-based Oncology Clinical Trial Matching
What You Should Know: – Today, Deep Lens and Cardinal Health announced a strategic collaboration that will integrate Deep Lens’ AI-based clinical trial matching solution, […]
Measuring the Value Healthy Individuals Place on Generous Insurance Coverage of Severe Diseases
That is the title of a paper I just published at Value in Health with Suepattra G. May, Lauren M. Zhao, Katalin Bognar, Yong Yuan, […]
Is Cocamidopropyl Betaine in Toothpaste Better Than Sodium Lauryl Sulfate?
For those with recurrent canker sores, is it better to use a toothpaste with SLS, CAPB, or no foaming agents at all? Sodium lauryl sulfate […]
A ‘Game Changer’ for Patients With Esophageal Cancer
A drug that unleashes the immune system offers a rare glimmer of hope for those with a cancer that resists most treatments.
mAbxience’s MB02 (biosimilar, bevacizumab) Receives EC’s Approval for the Treatment of Cancer
Shots: The EC has approved MB02 biosimilar to Avastin (Bevacizumab) in the EU for the treatment of carcinoma of the colon or rectum, BC, NSCLC, […]
Is Sodium Lauryl Sulfate (SLS) in Toothpaste Safe?
Just because the sodium lauryl sulfate in toothpaste doesn’t cause cancer doesn’t mean it can’t cause problems. Sodium lauryl sulfate (SLS) is a common detergent […]
A ‘Game Changer’ for Patients With Esophageal Cancer
A drug that unleashes the immune system offers a rare glimmer of hope for those with a cancer that resists most treatments.
A ‘Game Changer’ for Patients With Esophageal Cancer
A drug that unleashes the immune system offers a rare glimmer of hope for those with a cancer that resists most treatments.
COVID Exposed The Dire Need for Real-Time Healthcare Data Sharing
Birju Shah, Head of Product for Uber Health & Communities Nick Jordan, Founder and CEO, Narrative In a world where technology and Big Data can provide […]
Helpful Foods to Support People with Autism
The sulforaphane found in five cents’ worth of broccoli sprouts has been shown to benefit autism in a way no drug ever has in a […]
Getting a Prescription to Die Remains Tricky Even as Aid-in-Dying Bills Gain Momentum
Linda Heim knew her dad didn’t plan to wait for the cancer to kill him. For decades, he’d lived in Montana, which they’d thought was […]
Omega Healthcare Acquires himagine Solutions to Expand Global Delivery Model
What You Should Know: – Omega Healthcare, a provider of outsourced revenue cycle management and other healthcare support services, today announced the acquisition of himagine Solutions, a St. Louis based […]
Bristol Myers Squibb wins first CAR-T therapy approval in multiple myeloma
The FDA has approved a Bristol Myers Squibb cell therapy made by engineering a patient’s immune cells to target a cancer protein called BCMA. The […]
José Baselga, Who Advanced Breast Cancer Treatments, Dies at 61
He was a top executive at Memorial Sloan Kettering before resigning over payments from health care companies. He went on to lead cancer research at […]
To Advance Health Equity, Put Real-World Cancer Data to Work
Dr. Miller, Medical Director of CancerLinQ LLC Despite decades of scientific progress against cancer, access to treatment remains highly unequal. Some of the reasons — […]
José Baselga, Who Advanced Breast Cancer Treatments, Dies at 61
He was a top executive at Memorial Sloan Kettering before resigning over payments from health care companies. He went on to lead cancer research at […]
José Baselga, Who Advanced Breast Cancer Treatments, Dies at 61
He was a top executive at Memorial Sloan Kettering before resigning over payments from health care companies. He went on to lead cancer research at […]
COSMIC database matches drugs to cancer mutations
The world’s largest database of cancer mutations can now be used to link mutations with drug treatments in what promises to be a step forward […]
Cancer services should be rebuilt after COVID disruption, experts say
There is a pressing need for a joined-up cancer strategy to reverse the impact of the COVID-19 pandemic, according to a new report from the […]
NeoGenomics Acquires Precision Oncology Platform Trapelo Health for $65M
What You Should Know: – NeoGenomics, Inc., a provider of cancer-focused genetic testing services and global oncology contract research services announced it has reached an […]
Instil Bio’s upsized IPO raises $320M for clinical tests of TIL cancer cell therapy
Instil Bio, one of several companies developing tumor-infiltrating lymphocytes, will use its IPO cash to advance its clinical testing plans. Meanwhile, Finch Therapeutics and Gain […]
Novartis, Bristol Myers join $72M funding for startup’s cancer radiotherapy R&D
Aktis Oncology is developing cancer radiation treatments intended to more precise and potent compared to other radiotherapies. The startup is now out of stealth with […]
How do you get all the data quality benefits of eCOA in less time and at lower cost?
Upcoming oncology trial? Which oncology eCOA Package offers the best ability to capture reliable endpoint evidence to increase speed, reduce cost, and ensure consistency across […]
Benefits of Turmeric for Arsenic Exposure
What happened when turmeric curcumin was put to the test to see if it could reverse DNA damage caused by arsenic exposure? Arsenic is a […]
Achieving Financial Sustainability: A Connected Community of Care’s #1 Goal
Dr. Keith Kosel, Vice President at Parkland Center for Clinical Innovation (PCCI) “Show me the money!” No one old enough to have seen the 1996 […]
Nobody Wants Cancer. But a ‘Big C’ Label Has Surprising Upsides.
Classifying a rare blood disorder as a cancer opened new doors for disease investigation, treatment and hope for a cure.
Aveo Oncology’s kidney cancer drug gets FDA nod, 8 years after stinging rejection
In two pivotal studies years apart, Aveo Oncology’s drug tivozanib did not help kidney cancer patients live longer overall compared to the standard of care. […]
Are Lectins in Food Good or Bad for You?
Might lectins help explain why those who eat more beans and whole grains have less cancer? Lectins are to blame for the great “white kidney […]
Nobody Wants Cancer. But a ‘Big C’ Label Has Surprising Upsides.
Classifying a rare blood disorder as a cancer opened new doors for disease investigation, treatment and hope for a cure.
Takeda buys Maverick as T-Cell engager research hots up
Takeda is taking its option to buy the privately held biotech Maverick Therapeutics and its T-Cell engager cancer therapies for $525 million, as research into […]
How to Avoid Lectin Poisoning
How should we properly cook beans? In the 1800s, a compound was discovered in castor beans, which we would come to know as the first […]
Roche’s Tecentriq loses bladder cancer use as FDA crackdown continues
Roche’s Tecentriq is the latest medicine to fall foul of a crackdown by the FDA on drugs that have failed to live up to their […]
Novartis’ canakinumab falls short in phase 3 lung cancer trial
Novartis’ attempt to treat cancer with the anti-inflammatory drug canakinumab was always a long shot, but it’s nevertheless a disappointing feeling when things don’t work […]
The drug Fenbendazole can make tumors sensitive to radiotherapy just like agents of chemotherapy
Likewise, it was demonstrated by actualizing high throughput screening in-vitro framework that the drug fenbendazole is successful, not just against standard non-small cell lung cancer, […]
Roche to Withdraw Tecentriq Indication in Metastatic Bladder Cancer in the US
Shots: The company reported the voluntary withdrawal of the Tecentriq (atezolizumab) indication in the US for prior-platinum treated mUC, bladder cancer The withdrawal was made […]
BioIntelliSense Partners with Leukemia & Lymphoma Society for Continuous Monitoring in Clinical Trials
What You Should Know: –BioIntelliSense announced it has entered into a strategic partnership with The Leukemia & Lymphoma Society (LLS) to incorporate the BioSticker™ platform […]
Innovative, Non-Invasive Technologies Advanced Earlier Detection & Monitoring of Liver Disease
Jon Gingrich, CEO, Echosens North America Leveraging technological advances to facilitate new ways of engaging patients and integrating non-invasive technology into a liver disease program […]
Amgen in $1.9bn swoop for Five Prime and its gastric cancer drug
Amgen is to buy US biotech Five Prime Therapeutics for around $1.9 billion, adding a potential gastric cancer drug to its pipeline. The big pharma […]
Agilent to Acquire Resolution Bioscience for $695M
Shots: Resolution to receive $550M in cash at closing and ~$145M following the achievement of certain milestones. The transaction is expected to close in Apr’2021 […]
Dr. Gundry’s The Plant Paradox Is Wrong
A book purported to expose “hidden dangers” in healthy foods doesn’t even pass the whiff test. I started getting emails about The Plant Paradox, a […]
How digital health impacts the development and adoption of cancer immunotherapies [Sponsored]
In an interview, BrightInsight Co-founder and CEO Kal Patel, MD, offered a preview of the report, The Role of Digital Health in Immuno-oncology Therapy Development […]
Merck & Co axes Keytruda lung cancer niche amid FDA crackdown
Merck & Co has voluntarily withdrawn its Keytruda immunotherapy from a lung cancer niche in the US, amid a crackdown by the FDA on drugs […]
Connecticut Is Doling Out Vaccines Based Strictly on Age. It’s Simpler, but Is it Fair?
With covid vaccines expected to remain scarce into early spring, Connecticut has scrapped its complicated plans to prioritize immunizations for people under 65 with certain […]
NICE okays regular NHS funding for Novartis’ breast cancer drug Kisqali
NICE has recommended moving Novartis’ Kisqali (ribociclib) from interim funding arrangements to regular NHS reimbursement for certain previously treated breast cancer patients. In the final […]
Biotech Vividion lands $135M in crossover cash, paving a path to the public markets
Vividion Therapeutics has technology that enables it to develop drugs for “undruggable” disease targets. The Series C financing is a crossover round, an indication a […]
FDA to quickly review Incyte’s Jakafi in chronic GVHD
The FDA is to begin a fast review of Incyte’s Jakafi (ruxolitinib) for patients with chronic graft-versus-host disease (GVHD), which cannot be treated with steroids. […]
Sanofi’s immunotherapy Libtayo gets FDA not in first line lung cancer
Sanofi’s cancer immunotherapy Libtayo (cemiplimab) has a third US indication after the FDA approved it for certain untreated lung cancer patients. The approval in first-line […]
Limited access to cancer biomarker testing in Europe, report finds
There is limited access to biomarker testing for cancer in Europe, despite the huge potential of the technology to improve outcomes, according to a new […]
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
AstraZeneca pulls Imfinzi in bladder cancer, nearly one year after Phase 3 miss
AstraZeneca is withdrawing U.S. marketing of Imfinzi in bladder cancer after the drug failed a study required as a condition of its 2017 accelerated approval. […]
Zynteglo halt re-ignites viral vector safety concerns; analysts
Bluebird Bio’s decision to hit pause on the launch of Zynteglo for beta thalassaemia after two cases of cancer were seen in a clinical trial […]
AZ withdraws Imfinzi in US bladder cancer use after trial failure
AstraZeneca has suffered a setback after it voluntarily withdrew its cancer immunotherapy Imfinzi (durvalumab) in a bladder cancer indication in the US. AZ’s share price […]
Who Will Be the Next F.D.A. Chief?
Two leading contenders generate wider debate about the leadership needed to restore morale and scientific integrity to an agency battered by the politicized Trump administration.
Startup Ozette unveils AI approach to understanding the immune system
Ozette applies artificial intelligence to immune monitoring to gain greater insight into a cancer patient’s immune system. Beyond informing treatment decisions, the technology can guide […]
Astellas/Seagen prepare full US filing of bladder cancer drug Padcev
Astellas and Seagen have the data they need for a full licence for their bladder cancer drug Padcev in the US, based on trial results […]
BMS Collaborate with Molecular Templates to Develop Engineered Toxin Body Therapies for Cancer
Shots: MTEM to receive $70M up front and is also eligible to receive ~$1.3B as development, regulatory and sales milestone along with royalties on future […]
Cyteir adds $80M to steer to Phase 2 with lead cancer drug, then maybe an IPO
Phase 2 testing of Cyteir’s lead cancer drug candidate later is slated to start later this year. The Series C round of funding includes crossover […]
Does Nutritional Yeast Trigger Crohn’s Disease?
Is the exaggerated reaction of many Crohn’s disease patients to baker’s, brewer’s, and nutritional yeast just a consequence of their inflamed leaky gut, or might […]
Seagen and Genmab file ‘trojan horse’ drug with FDA for cervical cancer
Seagen and Genmab have announced they have filed their antibody-drug conjugate tisotumab vedotin with the FDA for patients with recurrent or metastatic cervical cancer. The […]
Health Plans Must Go Beyond the ONC Mandate and Prioritize Member Experience
Minal Patel, CEO of Abacus Insights Laurent Rotival, SVP, Strategic Technology Solutions & CIO, Cambia Solutions We are all frustrated when there’s a glitch with […]
A study to avoid chemotherapy in patients with early HER-2+ breast cancer
MEDSIR, a global company dedicated to independent clinical research in oncology, has initiated the PHERGain II clinical trial to demonstrate that in patients with HER2-positive […]
Why Cancer Registries are Part of America’s Fight for Racial Equality
Warren A Whyte, Ph.D., VP Scientific Partnerships at ConcertAI According to a 2019 study in the Proceedings of the National Academy of Sciences, one in […]
Gene Screenings Hold Disease Clues, but Unexplained Anomalies Often Raise Fears
When her gynecologist recommended genetic testing, Mai Tran was reluctant. “I didn’t really want to do it,” recalled Tran, who had just turned 21 and […]
Bristol Myers lymphoma therapy acquired in Celgene deal wins FDA nod
After some setbacks and delays, the FDA approved Bristol Myers Squibb’s Breyanzi for certain lymphomas. It’s the third CAR T treatment to win the regulatory […]
Executive Hires: Walgreens Appoints New CEO, Cityblock Health, Innovaccer, Others
Walgreens appoints Rosalind (Roz) Brewer as the company’s Chief Executive Officer, effective on March 15, 2021. Brewer will also join the WBA Board of Directors […]
Sana Bio soars in stock market debut, raising $588M for cell & gene therapies
Sana Biotechnology is turning new science into novel medicines intended to overcome limitations of current cell therapies. After going from stealth to IPO in two […]
Treating Advanced Prostate Cancer with Diet
Dr. Dean Ornish showed that a plant-based diet and lifestyle program could apparently reverse the progression of prostate cancer for early stage, localized, watch-and-wait cancer. […]
Action needed to preserve the six protected classes
In the final hours of the previous Administration’s time in office, the Center for Medicare & Medicaid Innovation (the Innovation Center) (CMMI) announced new changes […]
A Patient Engagement Strategy Needs to Deliver a Holistic Experience
Chris Evanguelidi, Director, Enterprise Healthcare Market for Redpoint Global Inc. Researchers from Johns Hopkins published a study in October on the impact of the pandemic […]
Syapse Lands $68M to Expand Global Precision Oncology Data Sharing Network
What You Should Know: – Syapse raises 68M in equity investment led by Ally Bridge Group (ABG), with Northpond Ventures to expand delivery of real-world […]
Volpara Acquires Breast Cancer Risk Assessment Platform CRA Health for $18M
What You Should Know: – Volpara Health, an integrated breast care platform assisting in the delivery of personalized patient care has acquired breast cancer risk […]
StartUPDATES: New developments from healthcare startups
Check out news from healthcare startups including Carrum Health, Seven Bridges Genomics, Outcomes4Me and more.
AZ/Daiichi Sankyo’s partnership makes progress in lung cancer
AstraZeneca and Daiichi Sankyo have announced data from two drugs in lung cancer, which they are developing as part of their ongoing partnership. Results announced […]
Coconut Oil and the Boost in HDL “Good” Cholesterol
The effects of coconut oil were compared to butter and tallow. Even if virgin coconut oil and other saturated fats raise LDL “bad” cholesterol, isn’t […]
If I Have Cancer, Dementia or MS, Should I Get the Covid Vaccine?
As public demand grows for limited supplies of covid-19 vaccines, questions remain about the vaccines’ appropriateness for older adults with various illnesses. Among them are […]
Pandemic ‘pushed lung cancer services back 20 years’, doctors warn
Governments must act to restore the damage done to lung cancer services during the pandemic in order to reduce further avoidable deaths, according to a […]
Careology joins forces with remote care support firm RedArc
Digital cancer care platform Careology has joined forces with RedArc, which provides long-term support for people with serious illnesses. RedArc has a team of registered […]
To Beat COVID-19, We Need A Modern Approach to Public Health Data
Ed Simcox, Chief Strategy Officer at LifeOmic The COVID-19 pandemic, which has taken 270,000 American lives to date, has shined a light on another crisis […]
ICYMI: Cancer death rate continues decline due to advances in treatment
For the second year in a row, The American Cancer Society (ACS) reports a record single-year decline in cancer death rates in the United States. […]
Do the Pros of Brown Rice Outweigh the Cons of Arsenic?
Are there unique benefits to brown rice that would justify keeping it in our diet despite the arsenic content? For years, warnings had been given […]
AZ/Daiichi Sankyo’s Enhertu gets second US cancer indication
AstraZeneca and Daiichi Sankyo’s Enhertu cancer drug has picked up a second indication, in patients who have stomach cancer and haven’t responded to Roche’s Herceptin […]
Ex-Merck & Co scientist accused of stealing trade secrets could face jail
A former Merck & Co scientist could face up to 10 years in prison after he was accused of stealing trade secrets relating to drugs […]
FCC Unveils 14 Initial Projects Selected for $100M Connected Care Pilot Program
What You Should Know: – FCC announces initial 14 pilot project selected for $100M Connected Care Pilot Program that will support connected care service across […]
NICE recommends interim funding for GSK’s Zejula in ovarian cancer
Women with newly-diagnosed advanced ovarian cancer have a new treatment option in England after NICE recommend interim funding for GlaxoSmithKline’s Zejula (niraparib) in final guidance. […]
Is White Rice a Yellow-Light or Red-Light Food?
Arsenic is not just considered to be a carcinogen; it’s also designated as a “nonthreshold carcinogen, meaning that any dose, no matter how small, carries […]
Large decline in cancer mortality
Last year, I published a paper that showed that cancer mortality rates fell by 24% between 2000 and 2016 and further that new cancer drugs […]
Treating cancer with precision: It’s time for host response rofiling
Host response can be identified by proteomic profiling, which involves analyzing a broad range of select proteins in a series of patient blood samples, with […]
Boehringer to investigate ‘dark antigens’ with UK cancer specialist Enara
Boehringer Ingelheim has signed a strategic collaboration with UK biotech Enara Bio, focused on finding ways to fight cancer using “dark antigens” in a deal […]
How Much Arsenic in Rice Is Too Much?
What are some strategies to reduce arsenic exposure from rice? Those who are exposed to the most arsenic in rice are those who are exposed […]
Birinapant licensing; AvantGen, IGM pairs up for anti-SARS-CoV-2 antibodies; BeiGene, Novartis to co-dvelop Tislelizumab; Valo raises USD190 M; Bluebird Bio Spins-off
Medivir, IGM Biosciences enters into an exclusive licensing agreement for Birinapant Medivir AB has entered into an exclusive licensing agreement with IGM Biosciences to receive […]
AstraZeneca Collaborates with Adaptive on Mapping Immune Response in Cancer
Shots: The companies collaborated to evaluate the use of immunoSEQ T-MAP, for which Adaptive will receive quarterly payments + sequencing and data mapping fees AstraZeneca […]
COVID-19 Deferrals Lead to 3 Major Conditions Payers/Providers Must Address in 2021
What You Should Know: – COVID-19 care deferrals lead to three major boomerang conditions that payers and providers must proactively address in 2021, according to […]
How Risky Is the Arsenic in Rice?
Getting rice down to the so-called safe water limit for arsenic would still allow for roughly 500 times greater cancer risk than is normally considered […]
Pfizer deal paves way for approval of ImaginAb’s cancer imaging tech
ImaginAb has signed a deal with Pfizer, which it hopes will help it to gather information necessary for approval of its tumour imaging agent as […]
Why cell therapy manufacture is a team sport
Louis van de Wiel, Vice President, Site Head EU Manufacturing, Kite, a Gilead Company, reveals the complexity that sits behind the process of individualised cell […]
Meaningful Use of Genomics Requires Informatics Beyond EMRs
Assaf Halevy, Founder and CEO of 2bPrecise Electronic medical records (EMRs) are widely expected to serve as a cornerstone technology that drives the delivery of […]
DaVita & RenalytixAI Partner for Early Risk Identification to Help Slow Kidney Disease Progression
What You Should Know: – RenalytixAI and DaVita announce a program partnership that aims to slow kidney disease progression and improve outcomes for the nation’s […]
2020’s Top 20 Digital Health M&A Deals Totaled $50B
Teladoc Health and Livongo Merge The combination of Teladoc Health and Livongo creates a global leader in consumer-centered virtual care. The combined company is positioned […]
Arsenic in Rice Milk, Rice Krispies, and Brown Rice Syrup
I recommend people switch away from using rice milk For kids and teens, the amount of arsenic flowing through their bodies was found to be […]
Patient-First Model: High Tech Meets High Touch for Individuals with Rare Disorders
Donovan Quill, President and CEO, Optime Care Industry experts state that orphan drugs will be a major trend to watch in the years ahead, accounting for […]
Arsenic in Infant Rice Cereal
When it comes to rice and rice-based products, pediatric nutrition authorities have recommended that arsenic intake should be as low as possible. “The US Food […]
BMS calls time on brain cancer trial as Opdivo misses second target
Bristol Myers-Squibb has put out another downbeat “update” announcement about its immunotherapy Opdivo in an aggressive form of brain cancer, saying that it looks unlikely […]
How to Cook Rice to Lower Arsenic Levels
Boiling rice like pasta reduces arsenic levels, but how much nutrition is lost? Cooking rice in a high water-to-rice ratio reduces toxic arsenic content, which […]
Agios’ cancer pipeline auction; uniQure’s gene therapy on hold; Ultragenyx, Mereo Deal; aTyr Pharma Trial
Servier Acquires Agios’ Cancer Portfolio in a USD 2 Billion Deal The year is a prime witness of pricey deals and acquisitions in the pharmaceutical […]
AZ’s Tagrisso gets new early lung cancer use in US
AstraZeneca’s Tagrisso (osimertinib) has been approved by the FDA in a new lung cancer indication that extends its use to a group of patients with […]
MacroGenics’ HER2 breast cancer drug Margenza approved in US
MacroGenics’ HER2-targeted breast cancer drug Margenza has been approved by the FDA, challenging several recently approved drugs with a narrow efficacy edge over Roche’s Herceptin […]
Amgen files KRAS trailblazer sotorasib with FDA for lung cancer
Amgen has filed its groundbreaking KRAS inhibiting drug sotorasib with the FDA for a group of lung cancer patients with an aggressive form of the […]
COVID-19 and Reductions in Cancer Mortality
That is the topic of a commentary I wrote with co-authors Joanna MacEwan and Farzad Ali, titled “Does COVID-19 Threaten the Progress Pharmaceuticals Have Made […]
Readers and Tweeters Defend Front-Line Nurses and Blind Us With Science
Letters to the Editor is a periodic feature. We welcome all comments and will publish a selection. We edit for length and clarity and require full names. […]
Which Rice Has the Least Amount of Arsenic: Black, Brown, Red, White, or Wild?
Brown rice contains more arsenic than white rice, but the arsenic in brown rice is less absorbable, so how does it wash out when you […]
Report: More than 1,300 medicines and vaccines in development to help fight cancer
Over the last 30 years, significant progress has been made in the fight against cancer. Researchers have expanded their understanding of how cancer develops and […]
Roche Launches Cobas PIK3CA Mutation Test for Patients with Advanced or Metastatic Breast Cancer
Shots: Roche launches the cobas PIK3CA mutation test for patients with advanced/ m-BC in countries accepting the CE mark The IVT test is a real-time […]
5 big healthcare lawsuits of 2020
Some of the biggest legal stories of the year include patients attempting to mount a class action lawsuit against Mayo Clinic after an employee improperly […]
Daiichi Sankyo and AZ’s Trastuzumab Deruxtecan Receives CHMP’s Recommendation for Approval to Treat HER2 Positive Metastatic Breast Cancer
Shots: The recommendation is based on a P-II DESTINY-Breast01 study assessing trastuzumab deruxtecan in patients with HER2 positive unresectable/ m-BC prior treated with trastuzumab emtansine […]
LeenTaaS Secures $130M for ML Platform to Help Hospitals Achieve Operational Excellence
What You Should Know: – LeanTaaS raises $130 million in Series D Funding to strengthen its machine learning platform to continue helping hospitals achieve operational […]
Pair Team Emerges Out of Stealth with $2.7M to Automate Primary Care Operations
What You Should Know: – San Francisco-based digital health startup Pair Team emerges out of stealth with $2.7M in seed funding backed by Kleiner Perkins, […]
What HCPs think about COVID-19’s impact on cancer
COVID-19’s knock-on effect on cancer patients is of concern by HCPs, with delayed or decreased diagnosis seen as a key worry. CREATION.co’s Lara Meyer explores […]
Cancer Risk from Arsenic in Rice and Seaweed
A daily half-cup of cooked rice may carry a hundred times the acceptable cancer risk of arsenic. What about seaweed from the coast of Maine? […]
FDA puts Bellicum’s cancer cell therapy trial on hold
The FDA has placed a clinical hold on a phase 1/2 trial of Bellicum’s cancer cell therapy BPX-601, following a patient death. Houston, Texas-based Bellicum […]
StartUPDATES: New developments from healthcare startups
Read news from healthcare startups Outcomes4Me, Specifica, Segmed, and more.
Exelixis takes $20m option Iconic/Zymeworks’ cancer ADC
Exelixis has taken a $20 million option to license in an antibody-drug conjugate cancer (ADC) drug from Iconic, with clinical trials expected to start next […]
The Effects of Too Much Arsenic in the Diet
Even at low-level exposure, arsenic is not just a class I carcinogen, but may also impair our immune function and increase our risk of cardiovascular […]
Merck KGaA signs DNA damage response cancer deal with Artios Pharma
Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The […]
Virtual Engagement During COVID Pushes Paradigm Shift for Physician Training and Patient Care
Shalini Shah, MD is Vice-Chair and Associate Professor, Department of Anesthesiology & Perioperative Care, and Enterprise Director of Pain Services, UC Irvine Health The dominant […]
Genmab axes development of AXL-targeting cancer drug enapotamab vedotin
Genmab has axed development of its pipeline cancer drug enapotamab vedotin after it failed to show enough activity in a proof-of-concept trial. The drug is […]
Why Was Chicken the Primary Source of Arsenic Exposure in Children?
What was the National Chicken Council’s response to public health authorities calling for the industry to stop feeding arsenic-based drugs to poultry? “Dietary practices influence our […]
Bio-Thera Reports MAA Submission to EMA for BAT1706 a Proposed Biosimilar to Avastin
Shots: The company has submitted an MAAA for BAT1706 to EMA. Bio-Thera seeks a commercial license for all approved indications of bevacizumab in the EU […]
Recent Executive Hires: CVS Health New President, Cleveland Clinic/Amwell Joint Venture Leadership, Others
Neela Montgomery, EVP & President at CVS Pharmacy/Retail CVS Health Corporation names Neela Montgomery Executive Vice President and President of CVS Pharmacy/Retail, effective November 30, […]
Novartis set to overcome $14 billion patent cliff say analysts
Novartis’ pipeline is strong enough to overcome a $14 billion patent cliff as blockbuster drugs face generic competition in the coming years, analysts have said. […]
New Legal Push Aims to Speed Magic Mushrooms to Dying Patients
Back in March, just as anxiety over COVID-19 began spreading across the U.S., Erinn Baldeschwiler of La Conner, Washington, found herself facing her own private […]
COTA Lands $34M to Drive Innovation in Oncology Using Real-World Data
What You Should Know: – COTA, Inc., a healthcare technology company that uses real-world data to bring clarity to cancer care, has secured $34M in […]
Volaris Group Acquires Clinical Workforce & Workflow Platform medaptus
What You Should Know: – Volaris Group acquires medaptus, a clinical workforce, and workflow solutions that empower healthcare delivery entities to achieve their desired patient, […]
Lead Pharma signs $308m deal to develop small molecule drugs with Roche
Lead Pharma has signed a potential 260 million euro ($308 million) deal with Roche to develop small molecule drugs for immune diseases. The deal will […]
The Antioxidant Power of Açaí vs. Apples
There are so many açaí products on the market now, from frozen pulp in smoothie packs to freeze-dried powder and supplements. How is it eaten […]
Fresh doubts over BMS’ merger payout as FDA delays key drug review
Holders of a risky “bet” on three Bristol-Myers Squibb drugs are looking increasingly unlikely to get their pay-out after the company said COVID-19 travel restrictions […]
GenesisCare, GE ink $130M partnership to enhance cancer, cardiac care
The cancer and cardiovascular care provider has teamed up with GE Healthcare, granting its 440 centers in the U.S., U.K., Spain and Australia access to […]
German biotech CatalYm raises €50 million for GDF-15 inhibitor immunotherapy
CatalYm has closed a €50 million ($59m) series B financing round to fund clinical studies of its immunotherapy targeting Growth Differentiation Factor 15 (GDF-15). The […]
Merck & Co/Eisai eye kidney cancer use for immunotherapy combination
Merck & Co and Eisai are to file results from a phase 3 trial testing a combination of the former’s immunotherapy Keytruda, combined with the […]
M&A: RxVantage Acquires onPoint Oncology to Expand Offering to Oncology Practices
What You Should Know: – RxVantage has acquired onPoint Oncology to provide cancer care teams with on-demand access to educational resources, reimbursement data, and analytics. – The acquisition of […]
NICE backs chemo-free CLL combination from AbbVie and Roche
Previously treated patients with chronic lymphocytic leukaemia (CLL) in England will get a chemotherapy-free treatment option after NICE recommended NHS funding for a combination of […]
Can Soy Prevent and Treat Prostate Cancer?
As I discuss in my video The Role of Soy Foods in Prostate Cancer Prevention and Treatment, a compilation of 13 observational studies on soy […]
New cancer drugs saved 1.3 million lives
That is the finding from a recent paper by myself and co-authors Joanna MacEwan, Syvart Dennen, Rebecca Kee, Farzad Ali, and Katharine Batt. An excerpt […]
Johnson & Johnson Innovation Launches 3 Collaborations to Advance Healthcare in China
Front row (left to right): Jian Chen, Vice President, Xian Janssen Pharmaceuticals; Dan Wang, Head, Johnson & Johnson Innovation, Asia Pacific; Sharona Tao, Leader, Communications […]
After two decades, NICE begins consultation on drug assessment methods
The UK’s drug cost-effectiveness body NICE has launched a public consultation, presenting the case for change about how it assesses medicines, medical devices and diagnostics. […]
Merck & Co buys cancer biotech VelosBio for $2.75bn
Merck & Co has agreed to buy California biotech VelosBio and its experimental cancer drug for $2.75 billion in cash. Known as MSD outside North […]
AstraZeneca and MSD’s Lynparza (olaparib) Receive EU’s Approval as 1L Maintenance Treatment for HRD-Positive Advanced Ovarian Cancer
Shots: The approval is based on a biomarker subgroup analysis of P-III PAOLA-1 study assessing Lynparza + bevacizumab vs bevacizumab alone as 1L maintenance treatment in […]
Fermented or Unfermented Soy?
As you can see at the start of my video Fermented or Unfermented Soy Foods for Prostate Cancer Prevention?, there is an enormous variation in […]
Be in the room: Turning patient engagement to patient centricity
After three brushes with cancer, Robert Weker understands the patient journey more than many – and he is determined to put that experience to good […]
AZ’s Q3 results disappoint – but COVID19 vaccine trial is still on track
AstraZeneca has posted an uninspiring set of quarterly results as it gears up for results from its closely watched coronavirus vaccine trial. AZ said in […]
FDA Extends RCA With COTA to Explore COVID’s Effect on Cancer
What You Should Know: – The FDA just extended its research collaboration agreement (RCA) with COTA, specifically looking at how COVID-19 is affecting cancer. – […]
Europe approves Roche’s Tecentriq liver cancer combination
The European Commission has approved Roche’s Tecentriq immunotherapy, in combination with its established cancer drug Avastin, for patients with the most common form of liver […]
Novartis Reports Results of Kisqali (ribociclib) in P-III MONALEESA-7 Study in Women with HR+/HER2- Advanced Breast Cancer
Shots: The pivotal P-III MONALEESA-7 study assessing Kisqali + endocrine therapy vs PBO + endocrine therapy, in pre- & perimenopausal women with HR+/HER2- advanced or […]
