Jounce shares crash after it abandons immunotherapy combination trial
Shares in Jounce Therapeutics are down sharply after it emerged that its immunotherapy combination with Bristol-Myers Squibb’s Yervoy will likely fail to produce results in […]
cancer
AstraZeneca and Fusion Collaborate to Develop and Commercialize Radiopharmaceuticals and Combination Therapies for Cancer
Shots: Fusion to receive up front, as well as development milestones and other payments. The companies will jointly discover, develop, and have an option to […]
Sanofi to acquire Kiadis and NK cell tech for $353 million
Sanofi is to acquire Kiadis, a biotech specialising in therapies based around ‘off the shelf’ natural killer (NK) cells, for 308 million euros ($353 million). […]
GSK’s Zejula (niraparib) Receives EC’s Approval as a Treatment in Advanced Ovarian Cancer
Shots: The approval is based on PRIMA study assessing Zejula (300mg qd), later amended to incorporate an individualised starting dose of Zejula (200 mg or […]
ANGLE raises £20m, eyes opportunity in immunotherapy trials
Liquid biopsy company ANGLE has raised £20m through a conditional placing on the London Stock Exchange which will be used to expand commercial opportunities. ANGLE’s […]
What White Blood Cell Count Should We Shoot for?
At the start of my video What Does a Low White Blood Cell Count Mean?, you can see what it looks like when you take […]
Exact Sciences buys cancer detection company Thrive for $2.15 billion
Stocks for Exact Sciences leaped 33% after it announced the acquisition of liquid biopsy rival Thrive and UK start-up Base Genomics. Exact Sciences said it […]
Toxic positivity and grief: The reality of living through cancer
Cancer doesn’t end when treatment stops – it’s a lifelong journey and people need support throughout, says patient advocate Megan-Claire Chase. No one gets through […]
FDA Grants AppliedVR Breakthrough Designation for Virtual Reality Chronic Pain Treatment
What You Should Know: – FDA awards AppliedVR Breakthrough Device designation for treating treatment-resistant fibromyalgia and chronic intractable lower back pain – AppliedVR’s EaseVRx program […]
Study finds biopharmaceutical innovation is responsible for 35% of the increase in life expectancy from 1990 to 2015
Medicines are responsible for more than a third of the improvement in life expectancy from 1990 to 2015, according to a recent study published in […]
JPC Taps Proscia to Modernize World’s Largest Human Tissue Repository
What You Should Know: – The U.S. government’s Joint Pathology Center, which houses the world’s largest human tissue repository, today announced that Proscia, a leading […]
Blue Cross NC Launches No-Cost Virtual Programs to Quit Smoking and Reverse Diabetes
What You Should Know: – Today, Blue Cross and Blue Shield of North Carolina partners with Carrot Inc. and Virta Health to help address two […]
What About the Trans Fat in Animal Fat?
The years of healthy life lost due to our consumption of trans fats are comparable to the impact of conditions like meningitis, cervical cancer, and […]
AstraZeneca’s Tagrisso (osimertinib) Receives the US FDA’s Priority Review for the Adjuvant Treatment of Patients with Early-Stage EGFR-Mutated Lung Cancer
Shots: AstraZeneca’s Tagrisso has received sNDA’s acceptance and has been granted PR in the US for the adjuvant treatment of patients with early-stage (IB, II, […]
FDA grants fast review for AstraZeneca’s Tagrisso in early-stage lung cancer
The FDA has granted a fast review for AstraZeneca’s Tagrisso oncology drug in certain patients with early-stage lung cancer. Results from the phase 3 ADAURA […]
COVID-19 tests prop up Roche as US biosimilars bite in Q3
Roche’s pharmaceutical revenues have been hit by falling sales in its pharma division in Q3 but a spike in demand for COVID-19 tests spared the […]
Fujifilm & Volpara Partner to Help Clinicians Determine Patient Breast Density
What You Should Know: – FUJIFILM Medical Systems U.S.A., Inc. and Volpara Solutions announced the extension of their partnership to provide mammography facilities and clinicians […]
Model-based Strategy to Guide the Choice of Clinical Doses for ADC
Chemotherapy has been a powerful method for fighting cancer for decades. One of the most effective therapies available, it is also known for weakening the […]
Seattle Genetics rebrands as Seagen as it expands business globally
The company has received FDA approvals for two cancer drugs in less than 12 months and announced partnerships with Merck last month for a Phase […]
How to Treat Polycystic Ovary Syndrome (PCOS) with Diet
Given the role that oxidant free radicals are thought to play in aging and disease, one reason fruits and vegetables may be so good for […]
Cleveland Clinic Names Top 10 Medical Innovations For 2021
Cleveland Clinic’s top clinicians and researchers present the top 10 medical innovations transforming medical advancements and new awards to recognize healthcare innovation. The list of […]
AWS, PHDA Collaborate to Develop Breast Cancer Screening and Depression Machine Learning Models
What You Should Know: – Amazon Web Services (AWS) and the Pittsburgh Health Data Alliance (PHDA) announce a collaboration to produce more accurate machine learning […]
Shock as FDA rejects Mesoblast’s Ryoncil in paediatric graft versus host disease
The FDA has rejected Mesoblast’s Ryoncil cell therapy for children with graft versus host disease, despite a recommendation to approve from a panel of expert […]
MD Anderson researchers find mechanisms behind CAR-T cells’ efficacy, toxicity
The findings may make it possible to identify a subset of patients who experience poorer outcomes or more serious side effects, especially neurotoxicity.
NVIDIA Develops AI Model to Accurately Predict Oxygen Needs for COVID-19 Patients
What You Should Know: – NVIDIA and Massachusetts General Brigham Hospital researchers develop an AI model that determines whether a person showing up in the […]
New Jersey Urology Launches First-Ever Urologic-Centric Epic EHR
New Jersey Urology What You Should Know: – New Jersey Urology (NJU) becomes the first urology-only group to launch a urologic-centric Epic electronic health record […]
FDA approves BMS’ Opdivo and Yervoy combination in first-line mesothelioma
Bristol-Myers Squibb’s immunotherapy combination of Opdivo and Yervoy has been approved in the US in a new indication for untreated mesothelioma, a rare but aggressive […]
Roche pays $200m for Vaccibody’s cancer vaccine drug
Roche’s Genentech unit has paid $200 million to develop an individualised cancer vaccine with Norwegian biotech Vaccibody, which focuses on targets known as neoantigens that […]
6 Reasons Why Ranitidine Is Harmful and How It Caused Cancer to Many
Ranitidine is a pharmaceutical drug that is categorized as a histamine antagonist, also called an H2 blocker, that has popularly been used to treat acid […]
Topical Lemon Balm Lotion for Alzheimer’s
Improving cognitive performance with aromatherapy in young, healthy volunteers is one thing, but how about where it really matters? As I discuss in my video […]
Katie Porter lambasts big pharma over cancer drug price hike using whiteboard calculations – video
US representative Katie Porter used her now-signature whiteboard as she questioned former Celgene CEO Mark Alles over the connection between the significant price hike for Revlimid, […]
NIH Taps PhysIQ to Develop AI-Based COVID-19 Digital Biomarker
What You Should Know: – physIQ has been selected by the National Institute of Health (NIH) to develop an innovative AI-based COVID-19 digital biomarker solution […]
The Role of Meat and Dairy Viruses in Cancer
“Nearly 20% of cancer cases arising worldwide can be linked to infectious agents, including viruses.” Seven viruses are now conclusively tied to human cancers, and, […]
Triumvira Immunologics raises $55M in Series A funding round for new form of cancer cell therapy
The company hopes to use the money to bring its T-cell antigen coupler cell therapy technology – currently in preclinical development – into human clinical […]
TIGIT Therapies Digital Summit
The TIGIT checkpoint has gained much attention in recent years due to the number of roles it plays in several malignancies. TIGIT’s diverse function in multiple cell […]
The Coronavirus Crisis’ Silent Death Toll: Chronically Ill Patients
Dr. Kayur Patel, Chief Medical Officer of Proactive MD The impact of the coronavirus crisis is shining a bright light on many of the challenges […]
NICE recommends regular NHS funding for Roche’s lymphoma drug Polivy
NICE has recommended regular NHS funding for Roche’s Polivy in certain lymphoma patients in final draft guidance, overturning a previous rejection. The new guidance recommends […]
Gilead invests another $145M into expanded oncology pact with Tango Therapeutics
The update to the partnership includes opt-in rights for Gilead on 15 drug targets, up from five under the original 2018 deal. Gilead will pay […]
Food Combining for Prostate Cancer
What would happen if you secretly gave cancer patients four of the healthiest foods? In my video Pomegranate vs. Placebo for Prostate Cancer, I discussed […]
AZ aims to cut cancer clinic visits with new Imfinzi regimen
The FDA is to review data supporting AstraZeneca’s Imfinzi (durvalumab) cancer immunotherapy in a new four-week regimen that will halve the number of required clinic […]
BMS signs $475m cancer immunotherapy deal with Dragonfly
Bristol-Myers Squibb has signed an agreement worth $475 million to develop a new form of cancer immunotherapy drug with US biotech Dragonfly Therapeutics. BMS is […]
CancerIQ Raises $5M to Expand Genetic Cancer Risk Assessment Platform
What You Should Know: – CancerIQ raises $5M in Series A funding led by HealthXVentures to accelerate the growth of its genetic cancer risk assessment […]
CancerIQ raises $4.8M Series A funding round for cancer precision health technology
The Chicago-based startup company plans to use the funding to further growth of its product offering and integration with EHRs and genetic testing partners.
What Explains the Egg-Cancer Connection
The reason egg consumption is associated with elevated cancer risk may be the TMAO, considered the “smoking gun” of microbiome-disease interactions. “We are walking communities […]
FDA, Syapse Expand Research to Generate Real-World Data Related to COVID-19 and Cancer
What You Should Know: The FDA and Syapse announce research collaboration expansion to address urgent public health challenges including supporting FDA’s goal of rapid understanding […]
GSK nabs FDA approval for first-in-class multiple myeloma drug
Blenrep, an antibody-drug conjugate, is the first drug approved for multiple myeloma that targets the antigen BCMA. Several other companies are also developing BCMA-targeting therapies […]
Protected: Predicting Cancer Drug Combinations That Work
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4 strategies to help your infusion center navigate Covid-19 uncertainty
When reviewing a return to normal operations, there is much to consider. Here are four approaches aimed at establishing a healthy pathway back to something […]
FDA approves GSK’s Blenrep for advanced multiple myeloma
The FDA has approved GlaxoSmithKline’s multiple myeloma drug Blenrep, a first-in-class potential blockbuster that will be used in advanced disease. Blenrep (belantamab mafodotin) has been […]
Armpit Shaving and Breast Cancer
Shaving before applying underarm antiperspirants can increase aluminum absorption. Could this explain the greater number of tumors and the disproportionate incidence of breast cancer in […]
Talis Awarded $25M NIH Contract for Point-of-Care COVID-19 Testing
What You Should Know: – Today, Talis Biomedical Corporation announced it has been awarded a $25M contract from the National Institutes of Health (NIH) as […]
Incyte/Morphosys take on CAR-Ts as lymphoma antibody Monjuvi approved in US
Incyte and Morphosys’ Monjuvi antibody therapy has been approved for certain patients with lymphoma, as the companies hope to provide a more convenient alternative to […]
Roche’s NTRK tumour-agnostic therapy Rozlytrek approved in Europe
Roche’s tumour-agnostic therapy Rozlytrek has been approved in the European Union for people with tumours with the NTRK mutation, meaning Bayer’s class rival faces competition […]
NICE backs kidney cancer combination from Merck KGaA and Pfizer
NICE has said a combination of Merck KGaA’s Bavencio and Pfizer’s Inlyta should be available as a first line option for kidney cancer patients for […]
Gilead loses $3.3bn in Q2, blaming COVID-19 and cancer drugs firm acquisition
Gilead has blamed a $3.3 billion loss in Q2 on its acquisition of immune-oncology company Forty Seven – but revenues are declining as the pandemic […]
What Exercise Authorities Don’t Tell You About Optimal Duration
Physical fitness authorities seem to have fallen into the same trap as the nutrition authorities, recommending what they think may be achievable, rather than simply […]
BMS ‘bet’ with Celgene shareholders in balance after CAR-T refile
Bristol-Myers Squibb and bluebird bio have refiled their CAR-T therapy for multiple myeloma, leaving the outcome of a three drug “bet” with former Celgene shareholders […]
Thrive raises $257M Series B round for registration study of blood test for early cancer detection
The study design is still being finalized, and the company is thus not yet divulging too many details. However, CEO David Daly said it would […]
The Crowding Out Strategy to Eating Healthier
It may be more expedient politically to promote an increase in consumption of healthy items rather than a decrease in consumption of unhealthy items, but […]
AstraZeneca, Daiichi Sankyo sign $6B deal for antibody-drug conjugate
The companies will share development and commercialization of DS-1062 in solid tumors. They already have a similar deal in place, the $6.9 billion agreement signed […]
Sorrento to Acquire SmartPharm and Develop Pipeline of Gene-Encoded Therapeutic Antibodies Targeting COVID-19 and Cancer
Shots: Sorrento enters into letter of intent to acquire SmartPharm and develops pipeline of gene-encoded therapeutic Ab, initiating with Sorrento’s STI-1499 or COVI-GUARD, currently preclinical […]
StartUPDATES: New developments from healthcare startups
Read about new developments from healthcare startups including HealCo, Eikonoklastes, Sidecar Health and more.
European regulators back Blueprint’s Ayvakyt for stomach tumours
European regulators have recommended a licence for Blueprint Medicines’ Ayvakyt (avapritinib), for adults with stomach tumours with certain mutations. Blueprint specialises in drugs that tackle […]
Careology launches digital platform to monitor cancer patient’s health
A digital platform allowing clinicians to remotely monitor cancer patients’ health in real time has been launched in the UK. Already available on iOS with […]
Pandemic and currency headwinds hurt Roche in first half
Roche has announced half-year results showing the COVID-19 pandemic affected sales of its key products, with currency headwinds also weighing on revenues. The Swiss pharma’s […]
Bacteria and Colon Cancer
Let’s catch on some non-coronavirus research today with an interesting approach against a very bad disease, metastatic colon cancer. This new paper (from groups at […]
Evotec Collaborates with Quantro Therapeutics to Discover and Develop Novel Therapies for Cancer and Other Diseases
Shots: The two companies collaborated to discover and develop novel therapeutics interfering with the disease-causing transcriptional programs in cancer and other diseases. Quantro intends to […]
Virtually or In-Person, Automation Improves The Healthcare Experience
Muthu Alagappan, MD, Medical Director at Notable Health The COVID-19 pandemic has caused an unprecedented shift in the way consumers view and access a variety of goods […]
Combating Air Pollution Effects with Food
There is a food that offers the best of both worlds—significantly improving our ability to detox carcinogens like diesel fumes and decreasing inflammation in our […]
Merck KGaA takes second option from cancer immunotherapy pact with F-Star
Germany’s Merck KGaA has taken an option on a second cancer immunotherapy drug from its development deal with Anglo-American biotech F-star Therapeutics. The companies signed a deal to develop cancer immunotherapies […]
Activ Surgical Raises $15M Advance Autonomous and Collaborative Surgery
What You Should Know: – Digital surgery pioneer Activ Surgical raises $15M in funding led by ARTIS Ventures to accelerate U.S. commercialization and European expansion […]
New report explores setbacks that bring future cancer success stories
Conversations and healthy debate about issues facing the biopharmaceutical industry and the health care system are critical to addressing the important work we do for […]
NICE backs NHS use for Astellas’ Xospata after rethink
NICE has recommended regular NHS funding for Astellas’ Xospata (gilteritinib) monotherapy for certain adult patients with acute myeloid leukaemia. In final draft guidance NICE said that the drug is recommended […]
FDA AdCom votes unanimously in favor of GSK myeloma drug, despite earlier agency skepticism
The Oncologic Drugs Advisory Committee voted 12-0 that the benefit-risk profile of belantamab mafodotin supported the drug. The vote came despite concerns expressed by the […]
Roche pays Blueprint $675M upfront for ex-U.S. development, commercialization rights to cancer drug
Under the deal, Blueprint will additionally be eligible for more than $900M in milestone payments plus royalties for the RET inhibitor pralsetinib. The deal includes […]
Paige Lands Additional $15M for AI-Native Digital Pathology Ecosystem
What You Should Know: – Paige secures an additional $15M from Goldman Sachs for a total Series B funding round of $70M for its AI-native […]
Pelvic mesh scandal is what happens when men with power ignore women | Richard Vize
Cumberlege report is a damning reminder of how arrogant, intimidating doctors have suppressed their patients’ views Julia Cumberlege’s report into avoidable harm inflicted by the […]
Philips and BioIntelliSense Integrate to Enhance Remote Patient Monitoring
What You Should Know: – Philips integrates the BioIntelliSense FDA-cleared BioSticker™ sensor as part of its remote patient monitoring solutions for patients outside the hospital. […]
What Does Drinking Soy Milk Do to Hormone Levels?
The vast majority of breast cancers start out hormone-dependent, where estradiol, the primary human estrogen, “plays a crucial role in their breast cancer development and […]
VelosBio raises $137M Series B round to support suite of ROR1-targeting cancer drugs
The company is currently running a Phase I study of its lead candidate, the antibody-drug conjugate VLS-101, in patients with lymphomas and leukemias. It has […]
FDA slaps hold on Cellectis’ off-the-shelf myeloma CAR-T trial after patient death
The patient, who had been enrolled in the Phase I study at the higher dose level of UCARTCS1A, suffered a cardiac arrest, the causes of […]
Are the BPA-Free Plastics Like Tritan Safe?
Do BPA-free plastics such as Tritan, have human hormone-disrupting effects? And what about BPS and BPF? Recent human studies indicate that exposure to the plastics […]
I believe Roundup gave me cancer. The Monsanto settlement is a slap in the face | Christine Sheppard
I have to inject myself with needles just to stay alive. Still, Bayer will continue to sell Roundup, and refused to label it as carcinogenic […]
Rising Popularity of Drug Targeting Synthetically Lethal Targets Fuels the Battle of PARP Inhibitors for Treatment of Advanced Cancer Indications
Cancer is considered to be the second leading cause of mortality, after cardiovascular diseases, accounting for every sixth reported death in the world. The International […]
Guest Post: Takeda seeks ‘new normal’ for cancer research during the COVID-19 pandemic
Conversations and healthy debate about issues facing our industry and the health care system are critical to addressing some of today’s challenges and opportunities. The […]
Chia Seeds vs. Flaxseeds
What effect do chia seeds have on weight loss, blood sugar, cholesterol, blood pressure, and inflammation? We’ve been eating chia seeds for more than […]
Medical Meat Bias
When famed surgeon Michael DeBakey was asked why his studies published back in the 1930s linking smoking and lung cancer were ignored, he had to […]
Using Green Tea to Help Prevent Cancer and Treat Cancer
Tea consumption is associated with a reduced risk of heart disease, stroke, and premature death in general, with each additional cup of green tea a […]
Does Aspartame Cause Lymphoma?
The approval of aspartame has a controversial history. The Commissioner of the U.S. Food and Drug Administration (FDA) concluded that “there is a reasonable certainty […]
What About the Sodium in Miso?
According to the second World Cancer Research Fund/American Institute for Cancer Research expert report, “[s]alt is a probable cause of stomach cancer,” one of the […]
How to Treat Endometriosis with Diet
“Endometriosis is a major cause of disability and compromised quality of life in women and teenage girls.” It “is a chronic disease which is under-diagnosed, […]
What to Eat and Avoid for Women with BRCA Gene Mutations
Five studies have been performed on breast cancer survival and soy foods involving more than 10,000 breast cancer patients, and together they found that those […]
