Merck picks circular path to RNA and commits $250M to biotech startup Orna
Merck aims to bolster its genetic medicines pipeline through a new research alliance with Orna Therapeutics, a startup whose technology forms RNA into a circle […]
mRNA
Gene silencing and mRNA: breakthroughs and barriers – the pharmaphorum podcast
On this week’s pharmaphorum podcast, editor in chief Jonah Comstock catches up with Dr. Marie Wikström Lindholm, SVP of molecular design at Silence Therapeutics. mRNA is a […]
Gene silencing and mRNA: breakthroughs and barriers – the pharmaphorum podcast
On this week’s pharmaphorum podcast, editor in chief Jonah Comstock catches up with Dr. Marie Wikström Lindholm, SVP of molecular design at Silence Therapeutics. mRNA is a […]
NIH starts trial of Moderna’s mRNA Nipah virus vaccine
Researchers in the US have started a clinical trial of a vaccine against Nipah virus, a serious infection caught from animals that has a fatality […]
Amgen joins Kernal Bio’s $25M financing as the startup brings mRNA 2.0 to cancer
Kernal Biologics has technology that enables the delivery of messenger RNA therapies to a wider range of destinations in the body. The Series A financing […]
Moderna facility in UK confirmed, part of 10-year deal with gov’t
Moderna has said it will open a new R&D and manufacturing facility in the UK which could lead to improved access by NHS patients to […]
Is making mRNA vaccines for infectious diseases profitable?
COVID-19 vaccines have had a huge beneficial impact on patient health. One study found that between December 2020 and June 2021, COVID-19 vaccines saved 240,000 […]
Moderna says new bivalent COVID-19 vaccine tops Spikevax
Moderna’s new version of its COVID-19 vaccine, which targets two virus variants including Omicron, has outperformed the company’s original Spikevax shot in a head-to-head clinical […]
Moderna’s HIV vaccine prepped for trials in Africa
Moderna has joined forces with non-profit organisation IAVI on a third phase 1 trial of its candidate HIV vaccine in Africa, where the burden of […]
AACR: BioNTech finds value in CAR-T/mRNA vaccine combo
Adding an mRNA vaccine to CAR-T cell therapy could be the key to unlocking activity in solid tumours, according to German biotech BioNTech. CAR-Ts have […]
Alnylam sues Moderna & Pfizer, claiming Covid-19 vaccines infringe lipid patent
Alnylam Pharmaceuticals has proprietary lipid nanoparticle technology used in its FDA-approved RNA therapies. The biotech company claims that the messenger RNA Covid-19 vaccines from Moderna […]
Alnylam sues Pfizer, Moderna over COVID-19 vaccines
Alnylam claims it is owed a slice of the massive revenues booked by Pfizer and Moderna for their mRNA-based COVID-19 vaccines, because they are both […]
Biotech startup Eclipse Bio emerges to shed light on RNA drug research
Scientists developing new RNA drugs need to understand how proteins bind to these molecules. Eclipsebio’s technology provides that analysis and the biotech startup now has […]
RNA biotech Nutcracker Therapeutics unshells $167M for drugs built on biochips
ARCH Venture Partners led the Series C round of financing for Nutcracker Therapeutics, a company developing new RNA drugs. The company’s process for developing and […]
Moderna targets 15 pathogens in ‘global public health strategy’
Moderna has unveiled plans to start clinical trials of mRNA-based vaccines for 15 infectious diseases that pose the biggest public health risks around the world […]
WHO announces international hub for mRNA vaccine training
The World Health Organization (WHO) announced the opening of a global biomanufacturing hub located in South Korea to provide training to low- and middle-income countries […]
LNP Formulation and Process Development in Pharma | April 12-14 2022
Embrace Technology Innovations to Optimise LNP Formulation, Alternative LNP Raw Materials, Process Control to Achieve Seamless Scale-Up, Compliance & Cost Effectiveness The inaugural LNP Formulation & […]
Pfizer, Moderna are prepping new vaccines for Omicron
With evidence growing that the current crop of COVID-19 vaccines are less protective against infection with Omicron, both Pfizer and Moderna have announced plans to […]
Beyond the pandemic: the potential of mRNA technology
The arrival of COVID-19 brought precious few positives, but one that emerged for the pharmaceutical industry was the emergence and validation of mRNA vaccine technology […]
Another mRNA company gets snapped up as Merck buys Exelead
The latest pharma company to make a move for an mRNA specialist is Germany’s Merck KGaA, which has offered a $780 million cash buyout to […]
Look out GSK, Pfizer and BioNTech are coming for Shingrix
GlaxoSmithKline places shingles vaccine Shingrix is among its top prospects, with peak sales potential of almost $6 billion. Now, Pfizer and BioNTech are joining forces […]
Chinese tech giant Baidu licenses mRNA algorithm to Sanofi
Sanofi has bolstered its push into mRNA-based therapies with a new licensing deal – but not as might be expected with some up-and-coming biotech company. […]
AZ, Moderna say mRNA drug is promising in heart failure
Moderna is already riding high on the strength of its mRNA-based COVID-19 vaccine, but the broader potential of its technology has been shown in a […]
Flagship’s next genetic meds startup has $50M for transfer at a critical protein stop
Alltrna, a biotech startup founded by Flagship Pioneering, is developing a new type of medicines based on a form of RNA called transfer RNA, or […]
FDA delays review of Moderna COVD jab in adolescents
The FDA has said it needs more time to review Moderna’s application for emergency use of its COVID-19 vaccine mRNA-1273 in children aged 12 to […]
RNA Therapeutics 2022
SMi Group’s 13th Annual Conference: RNA Therapeutics 2022 9th – 10th February 2022 London, UK www.therapeutics-rna.com/pharmaphorum Sponsored by: BIA Separations & eTheRNA Immunotherapies Bolstering the […]
Sanofi abandons mRNA COVID jab, despite positive trial
Sanofi has said that it won’t develop its mRNA-based vaccine for COVID-19 any further, even though it seemed to work in an early-stage trial, and […]
FDA authorizes Covid-19 booster shots, but only for the immunocompromised
Covid-19 vaccine booster shots are now authorized for organ transplant patients and others who have weakened immune systems. The FDA based its update on the […]
Sanofi’s mRNA strategy adds biggest piece yet with $3.2B Translate Bio buyout
Sanofi is acquiring Translate Bio, its messenger RNA R&D partner for the past three years, in a $3.2 billion deal. The pharmaceutical and vaccines giant […]
Sanofi swoops on partner Translate, buying the mRNA firm for $3.2bn
Sanofi has been forging ever-closer ties with its mRNA partner Translate Bio since the two started working together in 2018, and has now gone all […]
Sanofi to Acquire Translate Bio for ~$3.2B
Shots: Sanofi to acquire all outstanding shares of Translate Bio for $38.00/share in cash making a total equity value of ~$3.2B with a premium of […]
BioNTech’s mRNA vaccine drive now includes malaria, TB shots
Flushed with the success of its COVID-19 vaccine, BioNTech has pressed the accelerator on the development of shots for other infectious diseases, and now plans […]
EMA finds possible link between mRNA COVID jabs and myocarditis
The EU medicines regulator has said that there is some evidence to suggest a possible link between mRNA-based vaccines for COVID-19 and rare cases of […]
How connected IoT technology will deliver the promise of next-generation vaccines
Too many cold chain suppliers are still monitoring deliveries and storage compliance with paper-based documentation by individuals scanning thermometers every two hours. Such systems fall […]
mRNA: the Higgs boson of modern medicine?
Messenger RNA (mRNA) is a single-stranded molecule, which is complementary to the DNA strands of a gene. It plays a prominent role in the process […]
GSK Collaborate with CureVac to Develop Next Generation mRNA COVID-19 Vaccines
Shots: CureVac to receive $90.14M up front, $90.14M as milestones on the achievement of specific milestones. GSK will be the marketing authorization holder for the […]
Key takeaways from BioNTech CEO’s JPM presentation
Ugur Sahin presented a sweeping vision of the company’s goal to become a next-generation immunotherapy company leveraging the messenger RNA platform technology that has won […]
Merck KGaA Acquires AmpTec to Strengthen its mRNA Capabilities for Vaccines, Treatments and Diagnostics
Shots: The acquisition will integrate AmpTec’s PCR-based mRNA technology with Merck’s expertise in lipids manufacturing, providing combine offering across mRNA value chain The deal will […]
FDA panel backs use of Pfizer/BioNTech vaccine for Covid-19
The nonbinding recommendation is a final hurdle before an official emergency use authorization for the vaccine, which could be the first shot approved for use […]
New COVID vaccines could revolutionize vaccination
The post New COVID vaccines could revolutionize vaccination appeared first on Healthy Debate.
The known unknowns of COVID-19 vaccines
News that COVID-19 vaccines are up to 95 per cent effective has scientists cautiously optimistic. But questions remain. “There’s a long list of things we […]
Moderna to Seek the FDA and EMA’s EUA for mRNA-1273 and Shows 100% Efficacy in P-III COVE-Study
Shots: The P-III COVE study demonstrated 94.1% efficacy against COVID-19 and 100% efficacy against severe COVID-19. The vaccine was well tolerated with no serious safety […]
Moderna seeks COVID vaccine okay as data backs 94% efficacy
Moderna has said it will file for US, European and UK emergency approval of its coronavirus vaccine straight away, after reporting updated phase 3 results […]
Moderna Amends its Agreement with UK Government for an Additional 2M Doses of COVID-19 Vaccine
Shots: Moderna amended its current supply agreement with the UK govt. for an additional 2M doses of mRNA-1273 against COVID-19. The UK govt. has now […]
Is COVID the Rx for the Pharmaceutical Industry’s Reputation?
Darlene Dobry, Strategic Advisor, Medical Devices and Pharmaceuticals As the COVID-19 pandemic continues to bring the world’s economies, healthcare systems, and communities to their knees, […]
Insights+ KOL Articles: The New Normal and Covid-19 Vaccine Development
Since the virus outbreak in China, all eyes are on the most awaited Covid-19 vaccine offering a glimmer of hope. Abide by social distancing, wearing […]
Pfizer and BioNTech Initiate P-II/III Global Study of its Lead mRNA Vaccine Candidate Against COVID-19
Shots: The companies commence global (Ex- China) P-II/III study to evaluate a modRNA candidate (BNT162b2, 30µg dose level in a 2 dose regimen) from their […]
