Ketamine Confusion
The ketamine story is an excellent example of why CNS drug discovery is. . .well, how would the HR department put it? Well-stocked with personal […]
The Central Nervous System
Protein Aggregation Diseases
If you have occasion to study neurodegeneration, you will be struck by how many terrible high-profile diseases in this area seem to share a common […]
Treatment With MDMA
A theme that I return to every so often on the blog is the degree to which we don’t understand the molecular mechanisms of psychiatric […]
Oligonucleotides And Their Discontents
I remember being at a chemistry meeting in New Jersey back in around 1990 or 1991, where a speaker mentioned in passing that most of […]
Slipping Into the Brain
We’ve got a lot of longstanding technical difficulties in the drug development business – things that we’d really like to be able to do, but […]
