The aim is to potentially uncover new AAV serotypes for patients, as Cure Genetics notes that the clinical applications of current AAV serotypes could offer limitations, such as low transduction efficiency, low tissue specificity and immunogenicity.
VELP features various modes of innovation, including a strategy of building a plasmid library with high complexity and an effective ratio. The AAV production protocol allows for high genome-capsid correspondence and quality production capacity. It also allows for a shorter process to find the proper AAV vectors with nearly all possibilities effectively covered, Cure Genetics states.
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