Estetrol/Drospirenone (Nextstellis) – A New Combination Oral Contraceptive

Date: 
June 28, 2021

Issue #: 

1627

Summary: 
The FDA has approved a combination oral
contraceptive containing the estrogen estetrol and the
progestin drospirenone (Nextstellis – Mithra/Mayne).
Estetrol is the first new estrogen to become available
in the US in 50 years. Drospirenone is available alone
(Slynd) and in combinations with the estrogen ethinyl
estradiol for prevention of pregnancy.