Microtissue system allows study of deadly lung disease

Amid the COVID-19 pandemic and rising air pollution levels, incidence of idiopathic pulmonary fibrosis is anticipated to rise, urgently increasing the need for strong model systems. Researchers describe a 3D cell culturing platform that allows study of lung fibroblasts and their microenvironment. The platform enables measurement of cell behaviors and microenvironment changes involved in the disease progression of IPF, and the platform’s size and simplicity make it suitable for use in high-throughput drug screening protocols.