IV Amisulpride (Barhemsys) for Postoperative Nausea and Vomiting

Date: 
December 28, 2020

Issue #: 

1614

Summary: 
The FDA has approved IV amisulpride (Barhemsys
Acacia), a selective dopamine-2 and -3 (D2/D3) receptor
antagonist, for prevention and treatment of postoperative
nausea and vomiting (PONV) in adults. It is the first
antiemetic to be approved for rescue treatment of
PONV in patients who have symptoms despite receiving
antiemetic prophylaxis. Oral formulations of amisulpride
are available in Europe for treatment of schizophrenia
and acute psychotic episodes.