ViiV Healthcare Presents Results of GSK3640254 (GSK’254) in P-IIa study for the Treatment of HIV at CROI

March 10, 2021 Auto Bot Clinical Trials, HIV, Positive, Presents, results, Treatment, ViiV Healthcare 0

Shots:

  • The P-IIa POC study involves assessing GSK3640254 (GSK’254, qd) in 34 treatment-naïve adults with HIV. The study is divided into 2 parts- in part 1, patients received GSK’254 (10/200mg) vs PBO for 10days and in part 2, patients got GSK’254 (40/80140 mg) vs PBO for 7days
  • The study showed the antiviral activity b/w dose and antiviral response with 140 & 200mg doses demonstrating the reduction in plasma HIV-1 RNA. The largest mean changes in viral load were -1.5 log10 & -2.0 log10 copies/ml with these doses respectively
  • These findings support its P-IIb study that evaluates GSK’254 as part of combination therapy for treatment naïve adults living with HIV

Click here ­to­ read full press release/ article | Ref: ViiV Healthcare | Image: ViiV Healthcare

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