Electrochemistry, Lots of Electrochemistry
My scientific roots are in synthetic organic chemistry, so I enjoyed this paper very much. It’s from a team of authors at Syngenta, GSK, and […]
Chemical News
The Mirror World
Now this is a paper that’ll make your head spin. It’s from the Zhu group at Tsinghua University, and the head-spinning will be both because […]
Temozolimide Is Explosive
Here’s some surprising information to learn about a drug that’s been around for decades. Temozolomide (TMZ) is a chemotherapy agent, used in several intractable conditions […]
Ei-ichi Negishi, 1935-2021
Earlier this month, organic chemist Ei-ichi Negishi died at the age of 85. I missed this event (I wasn’t posting during those few days) so […]
Novobiocin Returns? But Not as an Antibiotic.
Here’s some interesting work from Dana-Farber (earlier BioRxiv version here) that may turn into a rare example of repurposing an old drug, if it works […]
Chose Your Controls Wisely
I’ve been meaning to write about this paper (open access) on some problems with chemical probes, and now’s a good time. There was a well-known […]
Med-Chem Should Be Larger Than It Is
I’m really glad to see this Perspective article in the Journal of Medicinal Chemistry, not least because it hits on a theme that I emphasize […]
Weird Natural Product Time Again
So let’s take a break today by looking at some compounds that, to a good approximation, many synthetic organic chemists would agree shouldn’t even exist. […]
Ripping Out Amines
I’ve been meaning to write about this new synthetic organic chemistry paper, because it’s just so weird. That adjective probably needs a little explanation. The […]
Watery Worlds
One of the themes of chemistry over the last few decades has been the ability to pay attention to increasingly fine-grained details. We have new […]
New Electron Tricks in Synthetic Chemistry
One of specialties of Phil Baran’s group at Scripps the last few years has been electrosynthesis, which has a traditional hmm-interesting-turn-the-page reputation among most synthetic […]
Lab! Of! The! Future!
This is a good article at C&E News on the “lab of the future”, and I’ll go ahead and make the standard comment that this […]
Rotating Rings of Solvents
Now here’s a chemistry technique I don’t think I ever would have thought of. This new paper in Nature presents what could be a new […]
Generating Crazy Structures
I feel like a dose of good ol’ organic chemistry this morning, and a (virtual) meeting I attended yesterday gave me a paper to talk […]
New Drugs and New Structures
Here’s an interesting paper that’s just appeared in ACS Med. Chem. Letters. The authors (Todd Wills and Alan Lipkus, both working at Chemical Abstracts) have […]
Phosphine, Life, and Venus
Well, as a chemist – one who does amateur astronomy on the side, yet – it’s obligatory that I write about the phosphine on Venus […]
Robo-Chemist: The Latest Version
So let’s talk robotic chemistry experimentation – that always calms everyone right down, doesn’t it? This new paper in Nature from a group in Liverpool is […]
