Top 20 BioPharma Companies based on 2020 Total Revenue

• Despite having the global pandemic, the biopharma companies were involved in multiple M&A, licensing deals. The major focus of the year remains the production and distribution of vaccines to combat the COVID-19 globally
• All the companies on our list are on the front line to combat this global crisis. The top 20 companies on the ledger changed from their 2019 ranking, leading to major ups & downs in the positions.
• J&J remains at the top with a revenue of $82.50B, followed by Roche & Bayer with $65.95B & $50.62B as their revenue respectively. PharmaShots has compiled a list of the top 20 biopharma companies based on their 2020 total revenue

Biogen is a global biopharmaceutical company focused on discovering, developing and delivering worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases as well as related therapeutic adjacencies. In Mar’ 2020, Biogen acquired BIIB118 (CK1 inhibitor) from Pfizer, while in Oct’2020 collaborated with Denali to co-develop & co-commercialize Denali’s LRRK2 inhibitors for PD.

Teva is a global pharmaceutical company that deals with g generics, specialty and over-the-counter products. In Jan’2020 and Mar’2020, the company launched Herzuma (trastuzumab-pkrb) which is biosimilar to Herceptin (trastuzumab), in Canada and the US, respectively.

Novo Nordisk is a global healthcare company, headquartered in Denmark. The company is a leader in diabetes and obesity care and has a strong presence in other chronic diseases such as NASH, CV and AD. In 2020, Novo Nordisk’s Rybelsus got approved in the EU, the UK and Japan.

The Merck Group, commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt. Its healthcare’s focus includes oncology, immuno-oncology, and neurology & immunology. In Jun’2019, the US FDA has approved IND for M5049 to treat Covid-19 pneumonia.

Boehringer Ingelheim is a research-driven biopharmaceutical company and has three core business areas: Human Pharma, Animal Health, and Biopharmaceutical Contract Manufacturing. Boehringer Ingelheim reinforced its position in immune-oncology therapies by acquiring shares in the Northern Biologics, which was subsequently renamed BI IO Canada.

Eli Lilly is an American pharmaceutical company headquartered in Indianapolis, Indiana. The company discovers, develop, manufacture, and market products in a single business segment i.e human pharmaceutical products.  In 2020, Baricitinib was granted EUA for suspected or laboratory confirmed COVID-19, in combination with remdesivir, in hospitalized adults and pediatric patients.

Gilead Sciences is a research-based biopharmaceutical company focused on the discovery, development, and commercialization of innovative medicines. In 2020, Gilead entered 18 partnerships and acquisitions to enhance its commercial portfolio and clinical pipeline across multiple therapeutic areas which include the acquisition of Immunomedics that added Trodelvy and other pipeline programs to our oncology portfolio.

Amgen is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. In Dec’2020, the US FDA has approved d Riabni, a biosimilar to Rituxan (rituximab), for adult patients with NHL, CLL, granulomatosis with polyangiitis and microscopic polyangiitis and was launched in the US in Jan’2021.

AstraZeneca is a global pharmaceutical focusing on Oncology; Cardiovascular, Renal & Metabolism and Respiratory & Immunology. In May’2020, AZ collaborated with RedX and got an exclusive global license to develop & commercialize RXC006 targeting fibrotic diseases including IPF.

Abbott Laboratories is an American multinational medical devices and health care company with headquarters in Illinois. It has four segments: Established Pharmaceutical Products, Diagnostic Products, Nutritional Products, and Medical Devices. The products in the pharmaceutical segment include Creon, Duphaston, Lipanthyl, TriCor, Serc, etc.

Pfizer Inc. is a research-based, global biopharmaceutical company. In Apr’2020, it collaborated with BioNTech to develop, manufacture and commercialize an mRNA-based coronavirus vaccine program, BNT162, aimed at preventing COVID-19 while in Nov’2020, it spun off Upjohn Business with Mylan, which created a new global pharmaceutical company, Viatris.

Bristol-Myers Squibb (BMS) is an American pharmaceutical company focused on oncology, cardiovascular, immunology, and fibrosis. In Oct’2020, BMS obtained a global exclusive license to Dragonfly’s IL-12 investigational immunotherapy program, including its extended half-life cytokine DF6002. The company completed the acquisition of MyoKardia & Forbius in Nov & Sept’2020 respectively.

Sanofi is a global healthcare leader in vaccines providing healthcare solutions in 170+ countries around the world. In 2020, Sanofi entered into multiple agreements which include its collaboration with Kiadis Pharma, Kymera Therapeutics, Principia Biopharma and has completed the acquisition of Synthorx for $68/ share in cash, representing an aggregate equity value of ~$2.5B.

AbbVie is a global, research-based biopharmaceutical company that develops therapies majorly for chronic autoimmune diseases, oncology, virology with additional targets like cystic fibrosis and women’s health and has an enriched pipeline in immunology and neuroscience. The company completed Allergan’s acquisition which enhances its growth platform.

GSK is a global healthcare company serving the world with drugs, vaccines & consumer healthcare products and is a leader in the areas of respiratory and HIV. In 2020, GSK collaborated with Sanofi to develop an adjuvanted COVID-19 vaccine and allied with VIR and Innovax to combat COVID-19.

Merck & Co. is a global health care company that delivers innovative health solutions through its prescription medicines, vaccines, biologic therapies, and animal health products. In Feb’2020, Merck announced its intention to spin-off products from its women’s health, biosimilars and established brands businesses into a new, independent, publicly traded company named Organon & Co. (Organon) through distribution of Organon’s publicly traded stock to the company shareholders. The spin-off is expected to be completed late in the Q2’21.

Novartis is a multinational group of companies specializing in research, development, manufacturing, and marketing with a broad range of healthcare solutions including generic and ophthalmic therapies. In Nov’2020, Novartis has secured a global license to Mesoblast’s cell therapy remestemcel-L in the treatment of COVID-19 while its Tabrecta got FDA’s approval for NSCLC with METex14 in May’2020.

Bayer is a leading life science firm with three divisions pharmaceuticals, consumer health, and crop science. In Sept’2020, Bayer completed the acquisition of 100% of the shares in biotech company KaNDy, further expanding its development portfolio in women’s health while in Dec’2020, it acquired Asklepios BioPharmaceutical.

Roche is a Swiss multinational healthcare company operating worldwide under pharmaceuticals and diagnostics divisions. In 2020, Roche initiated several approaches to fight against COVID-19. In Aug, Roche and Regeneron joined forces to develop, manufacture and distribute Regeneron’s Ab combination. In October, Roche and Atea collaborated to develop, manufacture, and distribute AT-527 targeting COVID-19 across the globe.

Johnson & Johnson (J&J) is an American multinational healthcare company focused on the development and commercialization of pharmaceutical, medical device, and consumer packaged products. In Sept’2020, J&J begun a P-III study of its COVID-19 vaccines and has received $1B in Federal Vaccine Production Funding. Additionally, J&J acquired Momenta Pharmaceutical for $7.5B in Aug’2020.

Sources: Company annual reports, SEC filings, press releases, and company websites.

Market Cap source: Google finance (as on 8^th April, 2021)

All revenues are reported in USD.

Note: Takeda is not included in the top 20 list, as its actual revenue is not available.

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Top 20 BioPharma Companies based on 2019 Total Revenue

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